RESUMO
Epithelioid angiomyolipoma is a recently recognized clinicopathologic entity first described by Martignoni et al. in 1995. Since then, several articles have further clarified its histogenesis and histologic features. Due to the presence of polygonal cells with voluminous cytoplasms, this neoplasm is often mistaken for renal-cell carcinoma. In this case presentation, we describe the cytologic features of an epithelioid angiomyolipoma obtained by fine-needle aspiration. The histogenesis and how it relates to diagnosis is briefly discussed. The importance of ancillary techniques in the differential diagnosis of epithelioid cells obtained in a renal aspirate is reviewed.
Assuntos
Angiomiolipoma/patologia , Células Epitelioides/patologia , Neoplasias Renais/patologia , Adulto , Angiomiolipoma/química , Angiomiolipoma/cirurgia , Antígenos de Neoplasias , Biópsia por Agulha , Carcinoma de Células Renais/patologia , Diagnóstico Diferencial , Células Epitelioides/química , Feminino , Humanos , Imuno-Histoquímica , Proteínas de Filamentos Intermediários/análise , Neoplasias Renais/química , Neoplasias Renais/cirurgia , Antígenos Específicos de Melanoma , Proteínas de Neoplasias/análiseRESUMO
OBJECTIVE: To review pregnancy-related changes in cervicovaginal smears and to distinguish them from neoplasia and dysplasia. STUDY DESIGN: One hundred consecutive abnormal cervicovaginal smears from pregnant women obtained during 1992-1993 were reviewed. Corresponding biopsies that were available were also reviewed for cytologic correlation. RESULTS: Sixty-one percent of cases showed inflammation changes, 21% contained low grade squamous intraepithelial lesion, and 9% had high grade squamous intraepithelial lesion. Diagnostic problems were encountered with decidual cells, Arias-Stella reaction and trophoblastic cells. CONCLUSION: Both the clinician and pathologist must be aware of diagnostic pitfalls and false positive diagnoses in pregnancy. Hence, it is extremely important that the clinician notify the pathologist about the pregnancy status of the patient.