Racial differences in coronary artery lesions: a comparison of coronary artery lesions between mainland Chinese and Australian patients.

AIMS: The purpose of this study was to compare coronary lesions in mainland Chinese and Australians using coronary angiography (CAG). METHODS AND RESULTS: 6251 suspected coronary heart disease (CHD) patients (3021 Chinese patients from Nanjing and 3230 Australian patients from Sydney) who underwent a CAG between January 1, 2001, and December 31, 2003, were studied. Of these, 69.4% Chinese and 75.5% Australians were diagnosed with CHD. The incidences of both left main coronary artery (LM) and left anterior descending branch (LAD) lesions in Australians were higher than that for Chinese of the same gender. In the same age range, above 40, Gensini scores of Australians were significantly higher than those of Chinese. CONCLUSION: In both Chinese and Australians, men had more severe coronary lesions than women. Comparison among different age ranges in the 2 ethnic groups shows that Australians typically have artery lesions more than 10 years earlier than mainland Chinese.

[Coronary artery lesion comparison between Chinese and Australian patients with coronary artery disease].

OBJECTIVE: To compare coronary lesion characteristics by coronary angiography (CAG) between yellows and whites. METHODS: CAG results of 3021 Chinese patients, defined as yellows, from Nanjing and 3230 Australian patients, defined as whites, from Sydney were analyzed. The coronary artery lesion was evaluated by the number and location of coronary lesion and Gensini scores. RESULTS: (1) Coronary stenosis was diagnosed in 69.4% Chinese patients and 75.5% in Australians. The involved coronary arteries were left anterior descending branch, right coronary artery, left circumflex branch and left main coronary artery in a descending order in both Chinese and Australians. (2) The incidences of three-vessel disease and left main disease of yellows were significantly lower than that of whites in both male (29.8% vs. 34.0% and 9.6% vs. 14.2%) and female patients (15.8% vs. 26.2% and 4.9% vs. 11.6%) respectively, all P < 0.05. (3) There was an age-dependent Gensini scores increase in both yellows and whites patients and Gensini scores at age 40 and more of whites were significantly higher than those of yellows in comparable age groups. CONCLUSION: The incidences of three-vessel disease and left main disease as well as Gensini score were significantly higher in Australian patients than those of Chinese patients.