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1.
J Equine Vet Sci ; 107: 103751, 2021 12.
Artigo em Inglês | MEDLINE | ID: mdl-34802627

RESUMO

The aim of this study was (i) to evaluate the relationship of climatic factors with gestational length (GL) and (ii) to evaluate the relationship of sire, foal gender and maternal factors with GL in mares. Retrospective data from 470 gestations of 202 respective mares were collected from a Criollo breeding farm in the southern hemisphere. GL was considered as the interval between ovulation and parturition. Climatic and environmental data (temperature, relative humidity, daily sunshine hours, precipitation, temperature humidity index - THI) were obtained daily and the mean values for foaling month and season were calculated. A multiple factor analysis of variance was performed to determine the relationship of the independent variables and interactions related to the mare, foal gender and stallion, and those related to the weather in each season of the year with GL as the dependent variable. The mean ± standard error (SE) of GL for the 470 gestations was 337 ± 0.4 days with a range of 311-363 days. Young-primiparous mares (340±0.9) had longer gestations (P < .001) than young-multiparous (336 ± 0.7) and mature-multiparous (334 ± 0.7) mares. Foal gender had no effect on GL. Gestational length was found to be affected by the stallion. Mares which experienced an autumn and winter gestational period with less daily sunshine hours had an increased GL (P < .05). In conclusion, environmental and climatic factors during pregnancy influenced the GL in mares, specifically, daily sunshine hours, precipitation and THI presented a negative correlation with GL. Young-primiparous Criollo mares presented longer gestational lengths than young or mature multiparous mares.


Assuntos
Clima , Prenhez , Animais , Parto Obstétrico/veterinária , Feminino , Cavalos , Masculino , Ovulação , Parto , Gravidez , Estudos Retrospectivos
2.
Rev. Hosp. Ital. B. Aires (2004) ; 40(3): 132-139, sept. 2020. ilus, tab
Artigo em Espanhol | LILACS | ID: biblio-1129139

RESUMO

Introducción: en 2014, tras más de 10 años de comenzada la Carrera de Medicina en el Instituto Universitario Hospital Italiano de Buenos Aires (IUHIBA), en la comunidad educativa se comenzó a plantear la necesidad de realizar un cambio curricular con el objetivo de lograr la enseñanza de habilidades complejas en forma integrada para generar un aprendizaje significativo y un mayor desarrollo de competencias. El cambio curricular comenzó a implementarse en 2018. Propósitos: describir la experiencia de diseño de las actividades de enseñanza en un currículo integrado. Desarrollo: para el diseño de las actividades de cada módulo (de un cuatrimestre de duración) se conformaron grupos planificadores multidisciplinarios. El objetivo principal de la planificación fue que los estudiantes comenzaran a desarrollar las habilidades necesarias para poder llevar adelante las actividades profesionales (EPAs: Entrustable Professional Activities) al final de la carrera. Los escenarios donde transcurren las actividades del Ciclo Inicial son las sesiones de aprendizaje basado en problemas, los laboratorios para el desarrollo de habilidades, las charlas plenarias y la atención primaria orientada a la comunidad. Fueron definidas EPAs para desarrollarse en el Ciclo Inicial, que guiaron la planificación en diálogo con los contenidos seleccionados para el cuatrimestre. Para poder realizar un diseño integrado se estableció la relación de cada actividad con las de los módulos precedentes, retomando y complejizando los contenidos para que el diseño fuera espiralado. Conclusiones: el mayor desafío de esta experiencia radicó en que debimos sumergirnos en un nuevo paradigma. El principal logro como grupo planificador fue hacer propia esta nueva forma de enseñanza: basada en el alumno, en problemas, integrada, espiralada. Evaluaremos los resultados tras su implementación y rediseñaremos las actividades, de ser necesario. (AU)


Introduction: in 2014, after 10 years of the establishment of the School of Medicine at the Instituto Universitario Hospital Italiano de Buenos Aires (IUHIBA), the educational community identified the need to make a curricular change to teach complex skills in an integrated way to generate meaningful learning and further development of skills. The new curriculum was implemented in 2018. Purposes: to describe our experience in designing teaching activities for an integrated curriculum. Development: multidisciplinary planning groups were formed to design the activities of each four-month module. The main objective was for students to develop the skills necessary to carry out professional activities (EPAs: Entrustable Professional Activities) by the time of graduation. The "Initial Cycle" activities took place in four scenarios: (i) problem-based learning; (ii) skills lab (iii) forum discussions; and (iv) communityoriented education. The EPAs that would be acquired in the Initial Cycle were selected. Those EPAs, together with the contents selected for the semester guided the planning groups. To ensure an integrated design, the relationships of each module with the preceding one were established. We adopted a spiral design where we returned to the same topics at a deeper level and with more complexity. Conclusions: the greatest challenge was that this experience involved a paradigm change. Our main achievement was to adopt a new form of teaching that was student and problem based, within an integrated and spiral curriculum. We plan to evaluate the results after implementation and redesign the activities, if necessary. (AU)


Assuntos
Humanos , Ensino/educação , Aprendizagem Baseada em Problemas/métodos , Argentina , Atenção Primária à Saúde , Faculdades de Medicina/tendências , Estudantes de Medicina , Ensino/tendências , Universidades/tendências , Técnicas de Planejamento , Competência Clínica , Aprendizagem Baseada em Problemas/tendências , Currículo/tendências , Capacitação Profissional
3.
Clin Respir J ; 12(7): 2220-2227, 2018 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-29570946

RESUMO

INTRODUCTION: Community-acquired pneumonia (CAP) is the infectious disease with the highest number of deaths worldwide. Several studies have shown an association between vitamin D deficiency and increases susceptibility to respiratory tract infections. OBJECTIVE: The aim of this study was to evaluate the serum 25-hydroxyvitamin D (25OHD) levels in hospitalized adults in general room with CAP. MATERIALS AND METHODS: An observational study was carried out in 207 hospitalized adults of both sex with CAP (>18 years) from Rosario city, Argentina (32° 52' 18″S) between July 2015 and June 2016. RESULTS: In total, 167 patients were included in the data analysis [59% women (57.4 ± 19.6 years), body mass index 27.2 ± 7.8 kg/m2 ]. In brief, 63% showed unilobar infiltrate and 37% were multilobar. The CURB-65 index was 66.5% low risk, 16.0% intermediate risk and 17.5% high risk. According to Charlson comorbidity index (CCI) 53.5% had not comorbidity (CCI = 0) and 46.5% showed CCI ≥ 1. The 25OHD level was: 11.92 ± 7.6 ng/mL (51.5%: <10 ng/mL, 33.5%: 10-20 ng/mL, 13.2%: 20-30 ng/mL and 1.8%: >30 ng/mL). Higher 25OHD were found in male (female: 10.8 ± 6.7 ng/mL, male: 13.5 ± 8.5 ng/mL, P = .02) and 25OHD correlated with age (r = -.17; P = .02). 25-Hydroxyvitamin D was also correlated with CURB65 index (r = -.13; P = .049), CCI (r = -.20, P = .007) and with the 10 years of life expectative (%) (r = .19; P = .008). In addition, higher 25OHD were found with lower CCI (CCI 0 = 13.0 ± 8.2 ng/mL, CCI ≥ 1= 10.5 ± 6.7 ng/mL; P = .0093). CONCLUSIONS: Hospitalized adults with CAP have lower 25OHD levels and would be associated with the severity of CAP.


Assuntos
Infecções Comunitárias Adquiridas/sangue , Pneumonia/sangue , Deficiência de Vitamina D/diagnóstico , Vitamina D/análogos & derivados , Adulto , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Argentina , Feminino , Hospitalização , Humanos , Masculino , Pessoa de Meia-Idade , Fatores Sexuais , Vitamina D/sangue
4.
Arch. argent. pediatr ; 115(4): 331-335, ago. 2017. graf, tab
Artigo em Inglês, Espanhol | LILACS, BINACIS | ID: biblio-887343

RESUMO

Introducción. La alergia a la proteína de la leche de vaca es la alergia alimentaria más frecuente en pediatría. El subtipo de las mediadas por inmunoglobulina E (IgE) presenta mayor riesgo de vida y peor pronóstico. Objetivos. Describir la evolución de la alergia a la proteína de la leche de vaca mediada por IgE y los factores de riesgo asociados a la persistencia de la enfermedad. Pacientes y método. Estudio descriptivo, retrospectivo en pacientes que consultaron a la sección de Alergia Pediátrica del Hospital Italiano entre junio de 2006 y junio de 2012 con diagnóstico de alergia a la leche de vaca mediada por IgE. Resultados: Se hallaron 72 pacientes con alergia a la leche de vaca mediada por IgE, 39 (54%) de sexo masculino. La edad promedio al momento del diagnóstico fue de 5,19 ± 3,7 meses; los síntomas de presentación más frecuentes fueron urticaria y vómitos. La rinitis y el asma fueron las enfermedades atópicas concomitantes más frecuentemente observadas. En el período de estudio, el 54,5% adquirieron tolerancia a la edad promedio de 32 meses. La presencia de pápulas mayores de 8mm en el prick test y de sensibilización a la caseína se asoció con la persistencia de la enfermedad. Conclusión. El 54,5% de los pacientes desarrolló tolerancia a los 32 meses de vida. Se encontró una asociación significativa entre el tamaño de la pápula al momento del diagnóstico y la sensibilización a la caseína con la persistencia de la enfermedad.


Introduction. Cow's milk protein allergy is the most common allergy in pediatrics. Immunoglobulin E (IgE)-mediated cow's milk allergy poses a higher risk for life and a worse prognosis. Objectives. To describe the course of IgE-mediated cow's milk protein allergy and risk factors associated with disease persistence. Patients and methods. This was a descriptive, retrospective study conducted in patients seen at the Division of Pediatric Allergy of Hospital Italiano between June 2006 and June 2012 who had been diagnosed with IgE-mediated cow's milk allergy. Results. Out of the 72 patients with IgE-mediated cow's milk allergy, 39 (54%) were boys. Patients' average age at the time of diagnosis was 5.19 ± 3.7 months old; the most common symptoms were urticaria and vomiting. Rhinitis and asthma were the most commonly observed concomitant atopic diseases. In the study period, 54.5% of patients developed tolerance at an average age of 32 months old. An 8-mm papule in the skin prick test and casein sensitization were associated with disease persistence. Conclusion. Overall, 54.5% of patients developed tolerance at 32 months old. A significant association was observed between papule size at the time of diagnosis and casein sensitization and disease persistence.


Assuntos
Humanos , Masculino , Feminino , Lactente , Imunoglobulina E/imunologia , Hipersensibilidade a Leite/imunologia , Argentina , Estudos Retrospectivos , Fatores de Risco , Tolerância Imunológica
5.
Arch Argent Pediatr ; 115(4): 331-335, 2017 Aug 01.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-28737860

RESUMO

INTRODUCTION: Cow's milk protein allergy is the most common allergy in pediatrics. Immunoglobulin E (IgE)-mediated cow's milk allergy poses a higher risk for life and a worse prognosis. OBJETIVES: To describe the course of IgE-mediated cow's milk protein allergy and risk factors associated with disease persistence. PATIENTS AND METHODS: This was a descriptive, retrospective study conducted in patients seen at the Division of Pediatric Allergy of Hospital Italiano between June 2006 and June 2012 who had been diagnosed with IgE-mediated cow's milk allergy. RESULTS: Out of the 72 patients with IgE-mediated cow's milk allergy, 39 (54%) were boys. Patients' average age at the time of diagnosis was 5.19 ± 3.7months old; the most common symptoms were urticaria and vomiting. Rhinitis and asthma were the most commonly observed concomitant atopic diseases. In the study period, 54.5% of patients developed tolerance at an average age of 32 months old. An 8-mm papule in the skin prick test and casein sensitization were associated with disease persistence. CONCLUSION: Overall, 54.5% of patients developed tolerance at 32 months old. A significant association was observed between papule size at the time of diagnosis and casein sensitization and disease persistence.


INTRODUCCIÓN: La alergia a la proteína de la leche de vaca es la alergia alimentaria más frecuente en pediatría. El subtipo de las mediadas por inmunoglobulina E (IgE) presenta mayor riesgo de vida y peor pronóstico. OBJETIVOS: Describir la evolución de la alergia a la proteína de la leche de vaca mediada por IgE y los factores de riesgo asociados a la persistencia de la enfermedad. PACIENTES Y MÉTODO: Estudio descriptivo, retrospectivo en pacientes que consultaron a la sección de Alergia Pediátrica del Hospital Italiano entre junio de 2006 y junio de 2012 con diagnóstico de alergia a la leche de vaca mediada por IgE. RESULTADOS: Se hallaron 72 pacientes con alergia a la leche de vaca mediada por IgE, 39 (54%) de sexo masculino. La edad promedio al momento del diagnóstico fue de 5,19 ± 3,7 meses; los síntomas de presentación más frecuentes fueron urticaria y vómitos. La rinitis y el asma fueron las enfermedades atópicas concomitantes más frecuentemente observadas. En el período de estudio, el 54,5% adquirieron tolerancia a la edad promedio de 32 meses. La presencia de pápulas mayores de 8mm en el prick test y de sensibilización a la caseína se asoció con la persistencia de la enfermedad. CONCLUSIÓN: El 54,5% de los pacientes desarrolló tolerancia a los 32 meses de vida. Se encontró una asociación significativa entre el tamaño de la pápula al momento del diagnóstico y la sensibilización a la caseína con la persistencia de la enfermedad.


Assuntos
Imunoglobulina E/imunologia , Hipersensibilidade a Leite/imunologia , Animais , Argentina , Bovinos , Pré-Escolar , Feminino , Humanos , Tolerância Imunológica , Lactente , Masculino , Estudos Retrospectivos , Fatores de Risco
6.
Rev. chil. obstet. ginecol ; 81(6): 511-514, dic. 2016. ilus, tab
Artigo em Espanhol | LILACS | ID: biblio-844525

RESUMO

La hemorragia intracraneal constituye una patología poco frecuente del embarazo y asociada a pobres resultados materno-fetales. Dentro de sus causas se encuentra, la preeclampsia severa, la cual aumenta la mortalidad en estas pacientes. Se presenta el caso de una gestante que acude al servicio de urgencias con síntomas neurológicos e hipertensión arterial, diagnosticándose preeclampsia severa, con realización de cesárea de urgencia. La tomografía de cráneo mostró hemorragia temporal izquierda, requiriendo manejo en cuidados intensivos con posterior estabilización y alta médica. La hemorragia intracraneal requiere un alto índice de sospecha, monitoreo intensivo y manejo multidisciplinario.


Intracranial hemorrhage is a rare complication during pregnancy, it is associated with poor maternal and fetal outcomes. Cerebral haemorrhage caused by pre-eclampsia increases mortality in these patients. We present the case of a pregnant woman who consulted to the service of urgencies with neurological symptoms and hypertension. Severe preeclampsia was diagnosed. She underwent successful emergent cesarean section. The brain scan showed a left temporal hemorrhage. She required intensive care management with subsequent stabilization and discharged from the hospital. Intracranial hemorrhage requires a high index of suspicion, intensive monitoring, and a multidisciplinary approach.


Assuntos
Humanos , Feminino , Gravidez , Adulto , Hemorragias Intracranianas/diagnóstico por imagem , Hemorragias Intracranianas/etiologia , Pré-Eclâmpsia/fisiopatologia , Complicações Cardiovasculares na Gravidez/etiologia , Complicações Cardiovasculares na Gravidez/diagnóstico por imagem , Tomografia Computadorizada por Raios X
7.
Arch Argent Pediatr ; 114(1): 30-5, 2016 Feb.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-26914072

RESUMO

INTRODUCTION: Latex allergy is one of the main reasons of anaphylaxis in the operating room. The prevalence of this condition is higher among patients with myelomeningocele. Epidemiological data obtained from Argentine patients is scarce. OBJECTIVE: To estimate the prevalence of latex sensitivity and latex allergy in a population of patients with myelomeningocele and to describe associated risk factors. POPULATION AND METHODS: Descriptive, cross-sectional, observational study. Family and personal history of allergy, number of surgeries, history of symptoms caused by having been in contact with latex or cross-reactive foods, eosinophil count, measurement of total immunoglobulin E and specific immunoglobulin E levels by means of skin and serologic testing for latex, aeroallergens and cross-reactive fruit. RESULTS: Eighty-two patients diagnosed with myelomeningocele were assessed: 41 were males and their average age was 15.3 ± 7.66 years old. Out of all patients, two did not complete skin and serologic testing. Among the remaining 80 patients, 16 (19.51%) had latex allergy, 46 (57.5%) were not allergic, and 18 (22%) showed sensitivity but not allergy. Having undergone more than five surgeries was a risk factor associated with latex allergy (p= 0.035). No significant association was observed with the remaining outcome measures. CONCLUSION: According to this study, the prevalence of latex allergy in this population of patients is 19.51% and the most important risk factor for this condition is a history of having undergone more than five surgeries.


INTRODUCCIÓN: La alergia al látex se encuentra dentro de las primeras causas de anafilaxia en el quirófano. La prevalencia de esta enfermedad es más elevada en pacientes con mielomenigocele. Existen escasos datos epidemiológicos en pacientes argentinos. OBJETIVO: Estimar la prevalencia de la sensibilidad y de la alergia al látex en una población de pacientes con mielomeningocele y describir los factores de riesgo asociados. PACIENTES Y MÉTODOS: Estudio descriptivo, transversal, observacional. Se analizaron los antecedentes familiares y personales de alergia, el número de procedimientos quirúrgicos, la historia de síntomas ante el contacto con látex o alimentos con reactividad cruzada, el recuento de eosinófilos, la inmunoglobulina E total y la inmunoglobulina E específica mediante pruebas serológicas y cutáneas para el látex, los aeroalérgenos y las frutas con reactividad cruzada. RESULTADOS: Se evaluaron 82 pacientes con diagnóstico de mielomeningocele, 41 del sexo masculino (50%), con edad promedio de 15,3 ± 7,66 años. Del total de los pacientes, 2 no realizaron las pruebas cutáneas y serológicas. De los 80 restantes, 16 (19,51%) presentaban alergia al látex, 46 (57,5%) no eran alérgicos y 18 (22%) fueron sensibles pero no alérgicos. Se observó que haber tenido más de 5 cirugías representaba un factor de riesgo asociado a alergia al látex (p= 0,035). No se encontró una asociación significativa con el resto de las variables evaluadas. CONCLUSION: El estudio estima que la prevalencia de alergia al látex en esta población de pacientes es de 19,51% y que el factor de riesgo más importante para el desarrollo de esta patología es el antecedente de haber sido sometido a más de 5 intervenciones.


Assuntos
Hipersensibilidade ao Látex/epidemiologia , Meningomielocele/complicações , Adolescente , Criança , Estudos Transversais , Humanos , Imunoglobulina E/sangue , Látex/efeitos adversos , Hipersensibilidade ao Látex/diagnóstico , Masculino , Prevalência , Testes Cutâneos , Adulto Jovem
8.
Arch. argent. pediatr ; 114(1): 30-35, feb. 2016. tab
Artigo em Inglês, Espanhol | LILACS, BINACIS | ID: biblio-838162

RESUMO

Introducción: La alergia al látex se encuentra dentro de las primeras causas de anafilaxia en el quirófano. La prevalencia de esta enfermedad es más elevada en pacientes con mielomenigocele. Existen escasos datos epidemiológicos en pacientes argentinos. Objetivo: Estimar la prevalencia de la sensibilidad y de la alergia al látex en una población de pacientes con mielomeningocele y describir los factores de riesgo asociados. Pacientes y métodos: Estudio descriptivo, transversal, observacional. Se analizaron los antecedentes familiares y personales de alergia, el número de procedimientos quirúrgicos, la historia de síntomas ante el contacto con látex o alimentos con reactividad cruzada, el recuento de eosinófilos, la inmunoglobulina E total y la inmunoglobulina E específica mediante pruebas serológicas y cutáneas para el látex, los aeroalérgenos y las frutas con reactividad cruzada. Resultados: Se evaluaron 82 pacientes con diagnóstico de mielomeningocele, 41 del sexo masculino (50%), con edad promedio de 15,3 ± 7,66 años. Del total de los pacientes, 2 no realizaron las pruebas cutáneas y serológicas. De los 80 restantes, 16 (19,51%) presentaban alergia al látex, 46 (57,5%) no eran alérgicos y 18 (22%) fueron sensibles pero no alérgicos. Se observó que haber tenido más de 5 cirugías representaba un factor de riesgo asociado a alergia al látex (p= 0,035). No se encontró una asociación significativa con el resto de las variables evaluadas. Conclusión: El estudio estima que la prevalencia de alergia al látex en esta población de pacientes es de 19,51% y que el factor de riesgo más importante para el desarrollo de esta patología es el antecedente de haber sido sometido a más de 5 intervenciones.


Introduction: Latex allergy is one of the main reasons of anaphylaxis in the operating room. The prevalence of this condition is higher among patients with myelomeningocele. Epidemiological data obtained from Argentine patients is scarce. Objective: To estimate the prevalence of latex sensitivity and latex allergy in a population of patients with myelomeningocele and to describe associated risk factors. Population and Methods: Descriptive, crosssectional, observational study. Family and personal history of allergy, number of surgeries, history of symptoms caused by having been in contact withlatex or cross-reactive foods, eosinophil count, measurement of total immunoglobulin E and specific immunoglobulin E levels by means of skin and serologic testing for latex, aeroallergens and cross-reactive fruit. Results: Eighty-two patients diagnosed with myelomeningocele were assessed: 41 were males and their average age was 15.3 ? 7.66 years old. Out of all patients, two did not complete skin and serologic testing. Among the remaining 80 patients, 16 (19.51%) had latex allergy, 46 (57.5%) were not allergic, and 18 (22%) showed sensitivity but not allergy. Having undergone more than five surgeries was a risk factor associated with latex allergy (p= 0.035). No significant association was observed with the remaining outcome measures. Conclusion: According to this study, the prevalence of latex allergy in this population of patients is 19.51% and the most important risk factor for this condition is a history of having undergone more than five surgeries.


Assuntos
Humanos , Criança , Adolescente , Imunoglobulina E/sangue , Testes Cutâneos , Prevalência , Estudos Transversais , Meningomielocele/complicações , Hipersensibilidade ao Látex/diagnóstico , Hipersensibilidade ao Látex/epidemiologia , Látex/efeitos adversos
9.
Artigo em Espanhol | LILACS, BINACIS | ID: biblio-1046830

RESUMO

La rama de la moral a la que incumbe el gobierno de los estados en cuanto arte, doctrina u opinión se conoce como política. Es un quehacer ordenado al bien común que se ocupa de la actividad por la cuallas personas que constituyen una sociedad libre resuelven los problemas que plantea su convivencia colectiva. Aquí, reflexiones, propuestas y dudas de un reconocido sanitarista.


Assuntos
Saúde Pública , Política de Saúde , Política de Saúde , Política
10.
Rev. med. Rosario ; 79(3): 130-135, sept.-dic. 2013. tab
Artigo em Espanhol | LILACS | ID: lil-707384

RESUMO

La rabdomiólisis se caracteriza por la destrucción de células musculares esqueléticas con liberacióndel contenido celular a la sangre. Sus causas son múltiples, y si bien una de las más frecuentes es el esfuerzo físicoextenuante, hay casos reportados tras practicar ejercicios de baja intensidad. Objetivo: reportar cuatro casos de rabdomiólisisinducida por ejercicio de baja intensidad. Pacientes y método: estudio descriptivo de una serie de cuatrocasos de rabdomiólisis inducida por ejercicio de baja intensidad, internados en un servicio de clínica médica entrelos años 2010 y 2012. Resultados: relación hombre/mujer 3/1, edad media 45.25 años (rango 29-58), media deduración de los síntomas hasta la consulta dos días (rango 1-3). El dolor fue el síntoma más relevante. Dos pacientespresentaron insuficiencia renal aguda con una media de duración de cuatro días (3-5). El tiempo medio hasta lanormalización de los valores de CPK fue de 8.75 días. La CPK media fue de 22.928,5 U/l (rango 1.415-65.672).Los cuatro pacientes recibieron hidratación parenteral vigorosa con solución salina y tuvieron buena evolución clínica.Conclusión: es importante considerar el diagnóstico de rabdomiólisis en pacientes que consultan por síntomasmusculares luego del ejercicio, incluso si éste fue de baja intensidad, pero ante la presencia de factores de riesgocomo hipokalemia, hidratación inadecuada, sudoración excesiva, temperatura ambiente y humedad elevadas. Elpronóstico de la rabdomiólisis es bueno cuando el cuadro es tratado en forma temprana.


Rhabdomyolysis is a syndrome characterised by the destruction of skeletal muscle, and release of cellular contentsinto the circulation. The causes vary; one of the most common causes is strenuous physical exercise, but there are reportsof the syndrome after practicing low-intensity exercises. Objective: to report four cases of low intensity exercise-inducedrhabdomyolysis. Patients and methods: descriptive study of a series of four cases with low intensity exercise-inducedrhabdomyolysis, admitted to the hospital between 2010 and 2012. Results: male/female ratio 3/1, mean age 45.25 years(range 29-58), mean duration of symptoms before consultation two days (range 1-3). The most important symptom waspain. Two patients presented with acute renal failure with a mean duration of four days (3-5). The average time untilthe normalization of CPK values was 8.75 days. The average CPK was 22,928.5 U/l (range 1,415-65,672). All patients creareceivedaggressive hydration with intravenous normal saline infusión, and had good clinical outcome. Conclusion: thediagnosis of rhabdomyolysis must be considered in patients who present with muscle symptoms after exercise, even if it wasof low intensity, especially in the presence of risk factors such as hypokalemia, inadequate hydration, excessive sweating, hotand humid weather. The prognosis of rhabdomyolysis is good when it is treated early.


Assuntos
Humanos , Adulto , Exercício Físico , Rabdomiólise/diagnóstico , Injúria Renal Aguda , Medicina Interna
11.
Rev. med. Rosario ; 79(3): 130-135, sept.-dic. 2013. tab
Artigo em Espanhol | BINACIS | ID: bin-130446

RESUMO

La rabdomiólisis se caracteriza por la destrucción de células musculares esqueléticas con liberacióndel contenido celular a la sangre. Sus causas son múltiples, y si bien una de las más frecuentes es el esfuerzo físicoextenuante, hay casos reportados tras practicar ejercicios de baja intensidad. Objetivo: reportar cuatro casos de rabdomiólisisinducida por ejercicio de baja intensidad. Pacientes y método: estudio descriptivo de una serie de cuatrocasos de rabdomiólisis inducida por ejercicio de baja intensidad, internados en un servicio de clínica médica entrelos años 2010 y 2012. Resultados: relación hombre/mujer 3/1, edad media 45.25 años (rango 29-58), media deduración de los síntomas hasta la consulta dos días (rango 1-3). El dolor fue el síntoma más relevante. Dos pacientespresentaron insuficiencia renal aguda con una media de duración de cuatro días (3-5). El tiempo medio hasta lanormalización de los valores de CPK fue de 8.75 días. La CPK media fue de 22.928,5 U/l (rango 1.415-65.672).Los cuatro pacientes recibieron hidratación parenteral vigorosa con solución salina y tuvieron buena evolución clínica.Conclusión: es importante considerar el diagnóstico de rabdomiólisis en pacientes que consultan por síntomasmusculares luego del ejercicio, incluso si éste fue de baja intensidad, pero ante la presencia de factores de riesgocomo hipokalemia, hidratación inadecuada, sudoración excesiva, temperatura ambiente y humedad elevadas. Elpronóstico de la rabdomiólisis es bueno cuando el cuadro es tratado en forma temprana.(AU)


Rhabdomyolysis is a syndrome characterised by the destruction of skeletal muscle, and release of cellular contentsinto the circulation. The causes vary; one of the most common causes is strenuous physical exercise, but there are reportsof the syndrome after practicing low-intensity exercises. Objective: to report four cases of low intensity exercise-inducedrhabdomyolysis. Patients and methods: descriptive study of a series of four cases with low intensity exercise-inducedrhabdomyolysis, admitted to the hospital between 2010 and 2012. Results: male/female ratio 3/1, mean age 45.25 years(range 29-58), mean duration of symptoms before consultation two days (range 1-3). The most important symptom waspain. Two patients presented with acute renal failure with a mean duration of four days (3-5). The average time untilthe normalization of CPK values was 8.75 days. The average CPK was 22,928.5 U/l (range 1,415-65,672). All patients creareceivedaggressive hydration with intravenous normal saline infusión, and had good clinical outcome. Conclusion: thediagnosis of rhabdomyolysis must be considered in patients who present with muscle symptoms after exercise, even if it wasof low intensity, especially in the presence of risk factors such as hypokalemia, inadequate hydration, excessive sweating, hotand humid weather. The prognosis of rhabdomyolysis is good when it is treated early.(AU)


Assuntos
Humanos , Adulto , Rabdomiólise/diagnóstico , Exercício Físico , Injúria Renal Aguda , Medicina Interna
12.
Rev. med. Rosario ; 79(1): 8-17, ene.-abr. 2013. graf, tab
Artigo em Espanhol | LILACS | ID: lil-695461

RESUMO

Introducción: una elevación extrema de la velocidad de eritrosedimentación (VES) es considerada cuando su valor es mayor o igual a 100 mm/hora y se asociaría con un bajo porcentaje de falsos positivos como indicador de enfermedad. Objetivos: conocer la frecuencia de aparición de elevaciones extremas de la VES y la frecuencia de las distintas enfermedades con las que este hallazgo se asocia en pacientes adultos que ingresan al servicio de clínica médica de un hospital de mediana complejidad. Pacientes y Método: se realizó un estudio descriptivo, observacional, de corte transversal, en el Hospital Juan Bautista Alberdi de la ciudad de Rosario, que incluyó a todos los pacientes que ingresaron al servicio de Clínica Médica entre el 01/03/2008 y el 30/04/2009 y que presentaron dentro de las 24 horas del ingreso una VES mayor o igual a 100mm/hora. Resultados: durante el período estudiado ingresaron 802 pacientes, de los cuales 39 (4,86%) presentaron una elevación extrema de la VES. La VES promedio fue de 117+-14,85 mm/hora, la relación hombre/mujer de 1.05/1 y la edad promedio 48.3+-16.3 años. Las causas asociadas con la elevación extrema de la VES fueron: infección (70.45%), enfermedad renal (9.09%), neoplasias (6.82%), enfermedades autoinmunes/otras inflamatorias no infecciosas (4.55%), causas misceláneas (4.55%) y sin diagnóstico (4.55%). Conclusión: la elevación extrema de la VES es un hallazgo relativamente frecuente que se constató casi en el 5% de los pacientes que ingresaron al servicio de Clinica Médica en el período de estudio, siendo su principal causa las enfermedades infecciosas.


Intoduction: an extreme elevation of erythrocyte sedimentation rate (ESR) is considered when its value is greater than or equal to 100 mm/hour, and it is associated with a low false positive rate as a sickness index. Objectives: to determine the frequency of extreme elevations of the ESR, and to determine the frequency of various diseases with which this finding is associated in adult patients who admitted to a medium complexity hostipal. Patients and Methods: it is a descriptive, observational, cross-sectional study which included all patients who were admitted to the Juan Bautista Alberdi Hospital between March 01, 2008 and April 30, 2009 and who presented within 24 hours of admission an ESR greater than or equal to 100 mm/hour. Results: during the study period 802 patients were admitted, of which 39 (4.86%) had an extreme elevation of the ESR. The average ESR was 117+-14.85 mm/hour, the male/female ratio 1.05/1 and the average age 48.3+-16.3 years. Causes associated with extreme elevation of the ESR included: infection (70.45%), renal disease (9.09%), neoplasms (6.82%), autoinmune diseases /other non-infectious inflammatory diseases (4.55%), miscellaneous causes (4.55%) and no diagnosis (4.55%). Conclusion: extreme elevation of the ESR is a relatively common finding; it was found in almost 5% of patients admitted to the hospital, and its main cause was an infectious disease.


Assuntos
Adulto , Reação de Fase Aguda , Sedimentação Sanguínea , Argentina , Doenças Transmissíveis , Estudos Transversais , Hospitais Municipais , Hospitalização , Medicina Interna , Proteínas de Fase Aguda
13.
Rev. med. Rosario ; 79(1): 8-17, ene.-abr. 2013. graf, tab
Artigo em Espanhol | BINACIS | ID: bin-130614

RESUMO

Introducción: una elevación extrema de la velocidad de eritrosedimentación (VES) es considerada cuando su valor es mayor o igual a 100 mm/hora y se asociaría con un bajo porcentaje de falsos positivos como indicador de enfermedad. Objetivos: conocer la frecuencia de aparición de elevaciones extremas de la VES y la frecuencia de las distintas enfermedades con las que este hallazgo se asocia en pacientes adultos que ingresan al servicio de clínica médica de un hospital de mediana complejidad. Pacientes y Método: se realizó un estudio descriptivo, observacional, de corte transversal, en el Hospital Juan Bautista Alberdi de la ciudad de Rosario, que incluyó a todos los pacientes que ingresaron al servicio de Clínica Médica entre el 01/03/2008 y el 30/04/2009 y que presentaron dentro de las 24 horas del ingreso una VES mayor o igual a 100mm/hora. Resultados: durante el período estudiado ingresaron 802 pacientes, de los cuales 39 (4,86%) presentaron una elevación extrema de la VES. La VES promedio fue de 117+-14,85 mm/hora, la relación hombre/mujer de 1.05/1 y la edad promedio 48.3+-16.3 años. Las causas asociadas con la elevación extrema de la VES fueron: infección (70.45%), enfermedad renal (9.09%), neoplasias (6.82%), enfermedades autoinmunes/otras inflamatorias no infecciosas (4.55%), causas misceláneas (4.55%) y sin diagnóstico (4.55%). Conclusión: la elevación extrema de la VES es un hallazgo relativamente frecuente que se constató casi en el 5% de los pacientes que ingresaron al servicio de Clinica Médica en el período de estudio, siendo su principal causa las enfermedades infecciosas.(AU)


Intoduction: an extreme elevation of erythrocyte sedimentation rate (ESR) is considered when its value is greater than or equal to 100 mm/hour, and it is associated with a low false positive rate as a sickness index. Objectives: to determine the frequency of extreme elevations of the ESR, and to determine the frequency of various diseases with which this finding is associated in adult patients who admitted to a medium complexity hostipal. Patients and Methods: it is a descriptive, observational, cross-sectional study which included all patients who were admitted to the Juan Bautista Alberdi Hospital between March 01, 2008 and April 30, 2009 and who presented within 24 hours of admission an ESR greater than or equal to 100 mm/hour. Results: during the study period 802 patients were admitted, of which 39 (4.86%) had an extreme elevation of the ESR. The average ESR was 117+-14.85 mm/hour, the male/female ratio 1.05/1 and the average age 48.3+-16.3 years. Causes associated with extreme elevation of the ESR included: infection (70.45%), renal disease (9.09%), neoplasms (6.82%), autoinmune diseases /other non-infectious inflammatory diseases (4.55%), miscellaneous causes (4.55%) and no diagnosis (4.55%). Conclusion: extreme elevation of the ESR is a relatively common finding; it was found in almost 5% of patients admitted to the hospital, and its main cause was an infectious disease.(AU)


Assuntos
Adulto , Sedimentação Sanguínea , Reação de Fase Aguda , Proteínas de Fase Aguda , Medicina Interna , Doenças Transmissíveis , Hospitalização , Estudos Transversais , Hospitais Municipais , Argentina
14.
Acimed (Impr.) ; 23(3): 279-294, jul.-set. 2012.
Artigo em Espanhol | LILACS-Express | LILACS | ID: lil-654505

RESUMO

La gestión de la ciencia y la innovación en las filiales universitarias municipales cubanas se ha convertido en un proceso de vital importancia para su perfeccionamiento y pertinencia social; sin embargo, son insuficientes los fundamentos teóricos existentes sobre esta temática y las herramientas metodológicas que se aplican para su desarrollo. El objetivo de este trabajo es mostrar una propuesta metodológica para la gestión sistémica de la ciencia y la innovación en una filial universitaria municipal cubana. Su aplicación en la Filial Universitaria Municipal "Ernesto Guevara", del municipio "Calixto García", en la provincia de Holguín, permitió mejorar significativamente los indicadores de este proceso y con esto se constató la efectividad de la metodología aplicada.


The management of science and innovation in cuban municipal university sites have become a process of vital importance for their improvement and social relevancy; however, the existent theoretical foundations about this thematic are insufficient and also the methodological tools that are applied for their development. The objective of this work is to show a methodological proposal for systemic management of science and innovation in a Cuban municipal university site, whose application in the Municipal University Site "Ernesto Guevara" of "Calixto García" municipality, in Holguín, allowed to improve significantly the indicators of this process and with it was verified the effectiveness of the applied methodology.

15.
ACIMED ; 23(3): 279-294, jul.-set. 2012.
Artigo em Espanhol | CUMED | ID: cum-53002

RESUMO

La gestión de la ciencia y la innovación en las filiales universitarias municipales cubanas se ha convertido en un proceso de vital importancia para su perfeccionamiento y pertinencia social; sin embargo, son insuficientes los fundamentos teóricos existentes sobre esta temática y las herramientas metodológicas que se aplican para su desarrollo. El objetivo de este trabajo es mostrar una propuesta metodológica para la gestión sistémica de la ciencia y la innovación en una filial universitaria municipal cubana. Su aplicación en la Filial Universitaria Municipal Ernesto Guevara, del municipio Calixto García, en la provincia de Holguín, permitió mejorar significativamente los indicadores de este proceso y con esto se constató la efectividad de la metodología aplicada(AU)


The management of science and innovation in cuban municipal university sites have become a process of vital importance for their improvement and social relevancy; however, the existent theoretical foundations about this thematic are insufficient and also the methodological tools that are applied for their development. The objective of this work is to show a methodological proposal for systemic management of science and innovation in a Cuban municipal university site, whose application in the Municipal University Site Ernesto Guevara of Calixto García municipality, in Holguín, allowed to improve significantly the indicators of this process and with it was verified the effectiveness of the applied methodology(AU)


Assuntos
Universidades , Instrumentos para a Gestão da Atividade Científica , Indicadores de Gestão/métodos , Inovação Organizacional
17.
Radiol Case Rep ; 7(2): 620, 2012.
Artigo em Inglês | MEDLINE | ID: mdl-27326279

RESUMO

A 37-year-old female with a large unruptured superior hypophyseal aneurysm underwent a guglielmi detachable-coil embolization after proper diagnostic three-dimensional digital subtraction angiography (DSA) of the internal carotid artery. Only a few case reports exist in the scientific literature about this uncommon entity that accounts for 1% of all intracranial aneurysms. We discuss the etiology, prevalence, and incidence of saccular intracranial aneurysms as well as their risk factors, prognosis, and differential diagnosis. We also review the literature on intracranial aneurysm and evaluate its current diagnostic management and therapeutic treatment.

19.
Neotrop Entomol ; 39(4): 464-9, 2010.
Artigo em Português | MEDLINE | ID: mdl-20877979

RESUMO

We aimed to compare the soil ant diversity in different land use systems from Atlantic Forest area, in Southern Bahia state, Brazil. The ants were sampled in 16 sites: two primary forest sites (un-logged forest); three young secondary forests (<8 years old); three intermediate secondary forests (8-20 years old); three old secondary forests (>20 years old); three Eucalyptus grandis plantations (3-7 years old), and two introduced pastures. Each site was sampled in three sampling points 15 m apart, and distant over 50 m from the site edge. In each sampling point we gathered the litter from a 1 m² and extracted the ants with Winkler extractors during 48h. We found 103 ant species from 29 genera and eight subfamilies. The five richest genera were Pheidole (19 species), Solenopsis (8), Apterostigma (10), Hypoponera (7) e Paratrechina (5). The highest ant richness density was found in the primary forest (7.4 species/sample; S = 37; n = 5); followed by the old secondary forest (5.33 species/sample; S = 48; n = 9); young secondary forest (5.25 species/sample; S = 42, n = 8); eucalyptus plantation (4.22 species/sample; S = 38, n = 9), intermediate secondary forest (3.5 species/sample; S = 35, n = 10, and introduced pasture (2.67 species/sample; S = 16, n = 6). The ecosystems with higher structural complexity showed the highest ant richness density by sample. Therefore, in the Atlantic Forest region, the eucalyptus plantation is a better alternative of land use to conserve the ant biodiversity than pastures, and quite similar to native secondary forests in ant community characteristics.


Assuntos
Formigas , Comportamento Animal , Animais , Brasil , Entomologia/métodos , Solo , Fatores de Tempo
20.
Nucl Med Commun ; 31(10): 859-63, 2010 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-20700066

RESUMO

PURPOSE: This study was carried out to determine the frequency, characteristics and possible causes and clinical significance of occasionally observed posterior layering of excreted 2-deoxy-2-[F]fluoro-D-glucose (F-FDG) in the bladder. PROCEDURES: A review of 567 consecutive patients referred for positron emission tomography/computerized tomography studies was performed. Urinary bladder size was measured in patients with and without layering. Urine samples from two patients with layering were imaged ex vivo. RESULTS: Twenty-four of 567 studies (4%) showed F-FDG posterior bladder layering. Mean volume+/-SD of the bladder was 175+/-161 ml in patients with layering and 93+/-83 ml in patients without layering. Urine samples collected from two randomly chosen patients with layering in vivo failed to show layering ex vivo. CONCLUSION: Posterior F-FDG layering occurs in 4% of positron emission tomography/computerized tomography cases and highly correlates with bladder volume. The mechanism is hypothesized to be because of slow F-FDG excretion in patients with a distended urinary bladder resulting in delayed mixing with urine, but needs to be further investigated with a more comprehensive study.


Assuntos
Fluordesoxiglucose F18/farmacocinética , Tomografia por Emissão de Pósitrons , Tomografia Computadorizada por Raios X , Bexiga Urinária/metabolismo , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Bexiga Urinária/diagnóstico por imagem , Bexiga Urinária/fisiopatologia , Urina , Adulto Jovem
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