Impact of intra-abdominal fat on surgical outcome and overall survival of patients with gastric cancer.

BACKGROUND: The aim of this study was to evaluate the impact of obesity on surgical outcome and prognosis in patients with gastric cancer. METHODS: A total of 304 patients who underwent curative gastrectomy for gastric adenocarcinoma between January 2005 and March 2008were enrolled. Body mass index (BMI) was calculated before the operation and visceral fat area (VFA) was measured by abdominal computed tomography (CT). The patients were divided according to BMI class and VFA quartile. The influence of BMI and VFA on surgical outcome and survival was evaluated. RESULTS: The median BMI was 23.3 kg/m(2) and the median VFA was 103 cm(2). There was a significant positive correlation between BMI and VFA. According to BMI class and VFA quartile, there were no significant differences in patients' characteristics or surgical outcome, with the exception of a significantly longer operation time and fewer retrieved lymph nodes in patients with a high BMI and VFA. The unadjusted overall and disease free survival were not significantly different between BMI classes or VFA quartiles. CONCLUSIONS: Obesity, as represented by BMI and VFA, may not be a poor prognostic factor in patients with gastric cancer.

The role of small intestinal bacterial overgrowth in postgastrectomy patients.

BACKGROUND: Small intestinal bacterial overgrowth (SIBO) is expected in postgastrectomy patients; however, its role has not been clarified. This study was to estimate the prevalence of SIBO and investigate the clinical role of SIBO in postgastrectomy patients. METHODS: This prospective study involved 76 patients who underwent gastrectomy for early gastric cancer with no evidence of recurrence. An H(2)-CH(4) breath test with oral glucose challenge test was performed to diagnose SIBO and dumping syndrome. Sigstad dumping questionnaires, serum glucose, hematocrit and pulse rate were simultaneously monitored for every 30 min for 3 hours. KEY RESULTS: There were significant differences in SIBO between the postgastrectomy patients and controls (77.6%vs 6.7%, P < 0.01). Abdominal fullness or borborygmus during oral glucose load were more common in SIBO-positive than in negative patients (50.8%vs 17.6%, P = 0.03), and were the independent factors for predicting SIBO in postgastrectomy patients (P = 0.02). The prevalences of dumping syndrome and hypoglycemia after oral glucose were 35 (46.1%) and 19 (25.0%), and were not different between both groups. However, the plasma glucose was significantly lower in SIBO-positive than in SIBO-negative patients at 120 and 150 min after oral glucose load (P < 0.05). No significant differences were observed in pulse rate and hematocrit in both groups. CONCLUSIONS & INFERENCES: SIBO is common among postgastrectomy patients. It appears to be associated with postprandial intestinal symptoms and might aggravate late hypoglycemia. SIBO could be a new therapeutic target for managing intestinal symptoms in postgastrectomy patients.

Estimates of net internal migration for Korea, 1985-90.

The authors "estimate the volume and rate of net internal migration in [South] Korea for each five-year age group for the period between 1985 and 1990, adopting the forward census survival ratio method.... Two sets of [estimates] are made: (1) net internal migration for administratively defined provinces and equivalent districts with urban-rural distinction and (2) net internal migration for each of 73 cities in 1990." Extensive tables contain the estimates.

Rural-urban migration and the social mobility of individuals in the Republic of Korea: an analysis of life history data.

PIP: The paper explores the impact of rural-to-urban migration on the social mobility of individuals, comparing rural-to-urban migrants with rural and urban natives. Using life history data from the 1983 Korean National Migration Survey, the authors examined the pattern of migrant adjustment by estimating the 1st difference form of the autoregressive equation. They found a disruptive effect of rural-to-urban migration that disappears gradually after migration. This study provides strong evidence that most rural-to-urban migrants successfully adapt to urban life through upward occupational mobility relative to both rural and urban natives. This finding sharply contrasts with previous studies on the urban informal sector, which emphasize selective rural-to-urban migration or the inability of migrating individuals to adapt to city life. Moreover, this study showed that a principle cause of the rapid expansion of Seoul is that migrants are more likely to be upwardly mobile when they are destined for Seoul rather than other cities.^ieng