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1.
Comput Biol Med ; 156: 106739, 2023 04.
Artigo em Inglês | MEDLINE | ID: mdl-36889025

RESUMO

In this work, we present a deep reinforcement learning-based approach as a baseline system for autonomous propofol infusion control. Specifically, design an environment for simulating the possible conditions of a target patient based on input demographic data and design our reinforcement learning model-based system so that it effectively makes predictions on the proper level of propofol infusion to maintain stable anesthesia even under dynamic conditions that can affect the decision-making process, such as the manual control of remifentanil by anesthesiologists and the varying patient conditions under anesthesia. Through an extensive set of evaluations using patient data from 3000 subjects, we show that the proposed method results in stabilization in the anesthesia state, by managing the bispectral index (BIS) and effect-site concentration for a patient showing varying conditions.


Assuntos
Anestesia , Propofol , Humanos , Anestésicos Intravenosos , Estudos de Viabilidade , Piperidinas , Anestesia Intravenosa/métodos , Eletroencefalografia
2.
Sci Rep ; 12(1): 1534, 2022 01 27.
Artigo em Inglês | MEDLINE | ID: mdl-35087165

RESUMO

It seems as though progressively more people are in the race to upload content, data, and information online; and hospitals haven't neglected this trend either. Hospitals are now at the forefront for multi-site medical data sharing to provide ground-breaking advancements in the way health records are shared and patients are diagnosed. Sharing of medical data is essential in modern medical research. Yet, as with all data sharing technology, the challenge is to balance improved treatment with protecting patient's personal information. This paper provides a novel split learning algorithm coined the term, "multi-site split learning", which enables a secure transfer of medical data between multiple hospitals without fear of exposing personal data contained in patient records. It also explores the effects of varying the number of end-systems and the ratio of data-imbalance on the deep learning performance. A guideline for the most optimal configuration of split learning that ensures privacy of patient data whilst achieving performance is empirically given. We argue the benefits of our multi-site split learning algorithm, especially regarding the privacy preserving factor, using CT scans of COVID-19 patients, X-ray bone scans, and cholesterol level medical data.


Assuntos
Algoritmos , Osso e Ossos/diagnóstico por imagem , COVID-19/diagnóstico por imagem , Colesterol/sangue , Hospitais , Privacidade , Estudos de Viabilidade , Feminino , Humanos , Masculino , Tomografia Computadorizada por Raios X , Raios X
3.
Sensors (Basel) ; 21(4)2021 Feb 20.
Artigo em Inglês | MEDLINE | ID: mdl-33672454

RESUMO

Green tide, which is a serious water pollution problem, is caused by the complex relationships of various factors, such as flow rate, several water quality indicators, and weather. Because the existing methods are not suitable for identifying these relationships and making accurate predictions, a new system and algorithm is required to predict the green tide phenomenon and also minimize the related damage before the green tide occurs. For this purpose, we consider a new network model using smart sensor-based federated learning which is able to use distributed observation data with geologically separated local models. Moreover, we design an optimal scheduler which is beneficial to use real-time big data arrivals to make the overall network system efficient. The proposed scheduling algorithm is effective in terms of (1) data usage and (2) the performance of green tide occurrence prediction models. The advantages of the proposed algorithm is verified via data-intensive experiments with real water quality big-data.

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