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Artigo em Inglês | MEDLINE | ID: mdl-23366052

RESUMO

Neuroscience research often requires direct access to brain tissue in animal models which clearly requires opening of the protective cranium. Minimizing animal numbers requests only well-experienced surgeons, since clumsy performance may lead to premature death of the animal. To minimise those traumatic outcomes, an algorithmic approach for closed-loop control of our Spherical Assistant for Stereotaxic Surgery (SASSU) was designed. Controlling the surgical robot's micro-drill unit by audio pattern recognition proved to be a simple and reliable way to automatically stop the automated drill feed. Sound analysis based on the anatomical morphology of a rat skull was used to train a Support Vector Machine (SVM) classification of the time-frequency representations of the drill sound. Fully automated high throughput animal surgeries are the goal of this approach.


Assuntos
Algoritmos , Craniotomia/instrumentação , Craniotomia/métodos , Robótica , Som , Animais , Ratos , Ratos Wistar
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