Current evidence of tissue engineering for dentine regeneration in animal models: a systematic review.

Aim: The aim of this study is to verify the type of scaffold effect on tissue engineering for dentine regeneration in animal models. Materials & methods: Strategic searches were conducted through MEDLINE/PubMed, Web of Science and Scopus databases. The studies were included with the following eligibility criteria: studies evaluating dentine regeneration, and being an in vivo study. Results: From 1392 identified potentially relevant studies, 15 fulfilled the eligibility criteria. All studies described characteristics of neoformed dentine, being that the most reported reparative dentine formation. Most of included studies presented moderate risk of bias. Conclusion: Up to date scientific evidence shows a positive trend to dentine regeneration when considering tissue engineering in animal models, regardless the type of scaffolds used.

Retrospective study on midfacial advancement in syndromic craniosynostosis: case series.

AIMS: The aim of this study was to evaluate elastic distraction surgical procedures performed on patients with syndromic craniosynostosis using cephalometric analyses. METHODS: Eleven patients who underwent surgical midfacial advancement were divided into three groups: G1 - monobloc frontofacial; G2 - Le Fort III; and G3 - high-level Le Fort I. The cephalometric analyses were manually created through cephalometric radiographs of each patient: T1 - preoperative; T2 - 6 months postoperatively; and T3 - 12 months postoperatively. The cephalometric landmark points were A and O. The distances between preoperative and postoperative tracings were measured. RESULTS: Point A advanced with no significant relapse 12 months after surgery. Point O advanced with a significant relapse rate of 28.5% postoperatively (p = 0.019). The vertical movement of points A and O increased by 40.6% (p = 0.033) and 38.8% (p = 0.032), respectively. There were no significant statistical differences between the assessed surgical techniques and syndromes with regard to midfacial advancement. CONCLUSION: Point O has presented statistically significant relapse only in horizontal movement after 12 months. The cephalometric analysis performed in the present study only suggested no differences between the studied surgical techniques and syndromes with regard to midfacial advancement in syndromic craniosynostosis.

Protocolo de regressão de parestesia após cirurgia de lateralização de nervo alveolar inferior / Surgical protocol for regression of paresthesia after inferior alveolar nerve lateralization

Objetivo: A cirurgia de lateralização do nervo alveolar inferior é pouco difundida devido ao dano neurossensor denominado pa restesia , causado pelo trauma ao feixe nervoso ocasionado pela manipulação cirúrgica. Este trabalho objetiva descrever um protocolo clínico com finalidade de regressão mais rápida da parestesia em pacientes atendidos no curso de especialização em Implantodontia da Unicastelo submetidos à cirurgia de lateralização do nervo alveolar inferior para a instalação de implantes odontológicos, aumentando a previsibilidade clínica da técnica. Materiais e métodos: neste estudo foi utilizado o aparelho de piezocirurgia para o acesso cirúrgico, soft laser para a bioestimulação e um composto polivitamínico para a regeneração tecidual. Resultados: Com a utilização do protocolo obteve-se uma expressiva redução da parestesia local, com retorno da sensibilidade nervosa em média de 20 dias. Dentro deste estudo, o melhor resultado de recuperação sensitiva foi obtido em oito dias pós-cirurgia, enquanto o mais lento ocorreu após seis meses e 21 dias devido a intercorrência de rompimento do feixe nervoso. Como dado comparativo, há 12 anos os pacientes submetidos à técnica cirúrgica apresentavam um quadro estatístico de retorno sensitivo com dois anos de espera. Conclusões: O protocolo de lateralização do nervo alveolar inferior adotado tem reduzido consideravelmente a incidência de parestesia. A utilização de piezocirurgia, "softlaser" e do composto polivitamínico associados a um bom conhecimento de anatomia e domínio da técnica cirúrgica são determinantes para o êxito do tratamento

Objective: The surgery of the inferior alveolar nerve lateralization has a restricted use because of the neurosensitive damage to the nerve bundle called paresthesia, caused by trauma during manipulation of the nerve for implant insertion. This paper aims to describe a clinical protocol with the purpose of the regression of paresthesia in patients enrolled in the specialization course of Implantology at University Unicastelo undergoing surgery of lateralization of the inferior alveolar nerve for dental implant place- ment, increasing the predictability of the clinical technique. Materiais and methods: In this work the piezoelectric device for the surgical approach, soft laser for biostimulation and a multivitamin compound for tissue regeneration were used to obtain a faster recovery of sensation. Results: Using the protocol we obtained a reduction of paresthesia, with consequent return of sensitivity to an average of 20 days, compared 12 years ago when the group began using the technique, where the average incidence of paresthesia was two vears The faster recovery of the area paresthesia in the study group was 8 days and longe r was 6 months and 21 days with the complication of rupture of the nerve bundle. Conclusions: The protocol adopted for inferior alveolar nerve lateralization has considerably reduced the incidence of paresthesia. The use of piezosurgery, softlaser and multivitamin compound associated with a good kno- wledge of anatomy and masterv of surgical technique are essential to the success of treatment