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1.
J Pharm Bioallied Sci ; 14(Suppl 1): S744-S747, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-36110681

RESUMO

Introduction: Fungal infections are rare occurrence in the oral cavity. They are most often seen in other medical conditions such as the immunocompromised states, diabetes, on immunosuppressants, and more recently, among the COVID patients. There are various ways that are employed to manage these infections. The most usual of fungal infection in these conditions is mucormycosis, also called as zygomycosis. Hence, in our study, we aim to evaluate the management of the fungal infection mucormycosis in trauma patients by the surgical approach. Materials and Methods: We piloted a retrospective observational study among 50 subjects who were admitted to the department with oral fungal infections with mucormycosis. We analyzed various clinical and demographic parameters among the subjects. The data thus obtained were analyzed with proper statistical tools deliberating P < 0.05 as significant. Results: We observed that among the 50 subjects, the mean age was 41 ± 1.7 years. There was no significant difference between the genders and the age groups. The most common reason for the oral involvement was uncontrolled diabetes. This was followed by malignancy, specifically leukemia, AIDS, and COVID. The most common site of the involvement was the palate, followed by the mandibular region. All the subjects tested positive for the fungal hyphae of Rhizopus arrhizus which was the most common of the species. The surgical debridement along with the medical management showed satisfactory results, while one death was noted in our study. Conclusion: Although rare, oral involvement in the fungal infection with the mucormycosis is often easily managed when diagnosed early. The proper surgical debridement is the best method of treatment along with the appropriate medications. The management of the underlying medical conditions is the primary key for the success of the treatments.

2.
J Pharm Bioallied Sci ; 14(Suppl 1): S980-S982, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-36110740

RESUMO

Objectives: The objective of the study is to compare xenograft graft material and synthetic bioactive glass allograft in immediate dental implant patients. Materials and Methods: Forty patients were grouped as Group A patients (xenograft graft material, BioOss) and Group B (synthetic allograft material, Perio Glas) and immediate implant placement was done. Plaque index, gingival index, probing depth, and bone resorption were compared at different intervals. Results: A nonsignificant difference was observed in all parameters at different interval of time (P > 0.05) recorded at mesial, distal, buccal, and lingual side. Conclusion: Xenograft (Bio Oss) and synthetic allograft (PerioGlas) found to be effective graft materials treatment choice.

3.
J Pharm Bioallied Sci ; 14(Suppl 1): S974-S976, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-36110753

RESUMO

Objective: The objective of the study is to compare two different implant designs having different neck configuration and neck interfaces. Materials and Methods: Fifty subjects were randomly divided into 2 groups, each containing 25 subjects. In Group I, conical connection (CC) (Nobel Biocare) with back-tapered collar dental implant and in Group II, external-hexagon (EH) (Nobel Biocare) with flat-to-flat implant-abutment interface dental implant was used. Radiographic marginal bone crest level and marginal bone loss (MBL) were compared. Results: A significant less MBL was seen in Group I compared to Group II recorded at different intervals of time (P < 0.05). Conclusion: CC implants with back-tapered collar exhibited less MBL as compared to EH implants with flat-to-flat implant-abutment interface.

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