Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 43
Filtrar
1.
Sci Rep ; 13(1): 14238, 2023 08 30.
Artigo em Inglês | MEDLINE | ID: mdl-37648819

RESUMO

The study aimed to reveal physical exercise conditions and catecholamine response-dependent differences while an individual experiences a flow state (FS) following noncompetitive and competitive running drills. Urine laboratory catecholamine levels were measured using a standard clinical method during pre- and post-physical exercises. The noncompetitive task involved intermittent running drills, from an absolute beginning up through exhaustion. Initially, the drill is performed individually then later competing alongside other runners. Twenty-two males (mean age: 40.27; SD: 5.4; min-max: 31-49 years) were selected in accordance to the following criterion: healthy status without using medication, routine forms of training (running, cycling or swimming) ideally performed with regularity, at least three times per week, 45 min per session. During the noncompetitive task, a high FS experience was associated with a low level of catecholamines, (noradrenaline and adrenaline) while in parallel, the high FS was associated with a low concentration of homovallinic acid. During competitive conditions, the FS-related catecholamine level changes have not yet been found. In conclusion, the low concentration of the circulating catecholamines supports the transient hypofrontality hypothesis regarding the FS experiences. Furthermore, synchronized noradrenaline and adrenaline neurosecretion play an essential role in the manifestation and the prolongation of FS in noncompetitive exercise conditions.


Assuntos
Corrida , Masculino , Humanos , Adulto , Epinefrina , Norepinefrina , Catecolaminas , Natação
2.
Front Psychol ; 14: 1176379, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37554131

RESUMO

Introduction: To understand the nature of hemispatial attention allocation in virtual reality (VR), a line bisection task (LBT) was administered both in a real environment and a virtual environment to assess the rate of pseudoneglect. The mental construction of real and virtual environments was assumed to increase visuospatial activity in right hemisphere-related cognitive processes; an alteration in the activity that manifests in the direction and rate of line bisection lateral error. Methods: In the present study, fifty-one right-handed healthy college students were recruited. They performed a line bisection task in real and virtual environments. Results: The obtained data showed that LBT errors in real and VR environments were correlated and individually consistent. Furthermore, a leftward LBT error was found in the physically real environment, however, in a VR the line bisection bias drifted towards the right hemispace. Participants with a lower right-handedness score showed a lower rate of left LBT bias in a real environment, but in VR, their LBT error showed a stronger rightwards error. Discussion: Participants showed an individually consistent pattern in both real and VR environments, but VR-induced visuospatial reality construction was associated with rightward LBT bias in a virtual environment.

3.
Acta Psychol (Amst) ; 230: 103735, 2022 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-36063587

RESUMO

Immersion in the digital environment has been widely researched; however, the effects of adaptive and maladaptive schizotypal personality traits on immersion have received relatively little attention up till now. This study investigates the factors of personal immersion while using entertainment and digital communication applications and other variables such as problematic internet usage, and Facebook addiction. The Immersive Tendency Questionnaire was applied to measure participants' tendency to experience artistic and life-like scenarios in traditional settings (reading a book and watching a movie) and digital environments (playing computer games and using the internet). The study was conducted with 717 college students and graduate persons including, 186 males (mean age: 28.49) and 531 females (mean age: 28.4). The results show that lowered focusing abilities are directly linked with deficiencies in self-coherence, and maladaptive behavior that manifests in problematic internet and Facebook usage. Furthermore, the attention/focusing ability during immersion is accompanied by coherent self-structure and psychological well-being. Therefore, for people who have adequate focusing skills and coherent self-structure, the usage of social media and computer gaming can be considered adequate digital tools for developing their cognitive and social skills.


Assuntos
Comportamento Aditivo , Jogos de Vídeo , Masculino , Feminino , Humanos , Adulto , Internet , Imersão , Comportamento Aditivo/psicologia , Jogos de Vídeo/psicologia , Personalidade
4.
Front Psychol ; 13: 931955, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35911018

RESUMO

This study explores the personal predispositions and dependencies while individuals use digital media and communication devices and analyses the statistical features of the Immersive Tendencies Questionnaire (ITQ) that is popular in assessing the personality trait-dependent reaction to mediated environments. The study evaluated 781 healthy graduates and postgraduates, of which 192 were men (average age: 28.6 years) and 589 were women (average age: 28.4 years). We applied several questionnaires to measure immersive tendencies in a mediated environment, adaptive and maladaptive personality predispositions, and problematic Internet use and Facebook addiction scales. We analyze the statistical features of the long and short forms of the Immersive Tendencies Questionnaire. The data obtained support the reliable usage of the short form of the instrument. The factor structure of the questionnaire presents dual facets. First, it indicates an absorptive and immersive tendency in any case of maladaptive tendencies. Second, it reflects an intensive capability to focus on the mediated environment with adequate cognitive control to avoid any contingency of being addicted. The short form of the ITQ is reliable and adequate to assess the relationship between the self-referred and environment-dependent psychological functions.

5.
Sci Rep ; 12(1): 12169, 2022 07 16.
Artigo em Inglês | MEDLINE | ID: mdl-35842454

RESUMO

Virtual reality (VR) technology has increased clinical attention in the health care of schizophrenia spectrum disorders in both diagnoses of the symptoms and assessment of schizotypal traits. However, the exact nature of VR-induced positive treatment effect in schizotypy is still unknown. In this study, VR technology was used as a non-invasive neurocognitive trigger to test the asymmetric visuospatial representational instability found in individuals with high schizotypy. The study aimed to reveal the brain functional hemispheric laterality in physical and virtual realities in individuals with schizotypal traits. Fifty-one healthy, right-handed participants (24 males and 27 females) were enrolled through public advertisements. Hemispheric functional asymmetry was measured by the Line Bisection Task (LBT). The results revealed that (a) LBT bias in the physical reality showed a handedness-related leftward pseudoneglect, however, similar handedness-related pseudoneglect in VR has not been found. (b) Comparing LBT bias in physically real and VR environments showed rightward drift in VR environments independently to the degree of handedness. (c) The schizotypy has no association with handedness, however, the cognitive schizotypy is related to the LBT bias. Higher cognitive schizotypy in VR associated with left hemispatial pseudoneglect. In conclusion, schizotypy is associated with ambiguous behavioral and cognitive functional laterality. In individuals with high cognitive schizotypy, the VR environment enhanced the representational articulation of the left hemispace. This effect may be originated from the enhancement of the right hemisphere overactivation and is followed by a lower mental control of the overt behavior.


Assuntos
Lateralidade Funcional , Transtorno da Personalidade Esquizotípica , Atenção , Computadores , Feminino , Lateralidade Funcional/fisiologia , Humanos , Idioma , Masculino
6.
Front Behav Neurosci ; 16: 763220, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35558438

RESUMO

The aim of this study was to reveal whether increased reward dependence (RD) plays a role in the catecholamine neurotransmitter release and testosterone hormone regulation during physical activities among healthy trained participants. Twenty-two male participants (mean age: 40.27 ± 5.4 years) participated in this study. Two conditions were constructed, namely, a noncompetitive and a competitive running task (RT), which were separated by a 2-week interval. Urine and blood samples were collected prior to and following the running tasks. Noradrenaline (NA), adrenaline (A), dopamine (D), and their metabolites, vanillylmandelic acid (VMA) and homovanillic acid (HVA), were measured from urine, while testosterone levels were analyzed from blood samples. RD was assessed using the Cloninger's Personality Inventory (PI). Mental health was evaluated using the WHO Well-Being, Beck Depression, and Perceived Life Stress Questionnaires. According to our findings, levels of NA, A, D, VMA, and testosterone released underwent an increase following physical exertion, independently from the competitive condition of the RT, while HVA levels experienced a decrease. However, we found that testosterone levels showed a significantly lower tendency to elevate in the competitive RT, compared with the noncompetitive condition (p = 0.02). In contrast, HVA values were higher in the competitive compared with the noncompetitive condition (p = 0.031), both before and after the exercise. Considering the factor RD, in noncompetitive RT, its higher values were associated with elevated NA levels (p = 0.007); however, this correlation could not be detected during the competitive condition (p = 0.233). Among male runners, the NA and testosterone levels could be predicted to the degree of RD by analyzing competitive and noncompetitive physical exercises.

8.
Sci Rep ; 12(1): 808, 2022 01 17.
Artigo em Inglês | MEDLINE | ID: mdl-35039541

RESUMO

The widely used rubber hand illusion (RHI) paradigm provides insight into how the brain manages conflicting multisensory information regarding bodily self-consciousness. Previous functional neuroimaging studies have revealed that the feeling of body ownership is linked to activity in the premotor cortex, the intraparietal areas, the occipitotemporal cortex, and the insula. The current study investigated whether the individual differences in the sensation of body ownership over a rubber hand, as measured by subjective report and the proprioceptive drift, are associated with structural brain differences in terms of cortical thickness in 67 healthy young adults. We found that individual differences measured by the subjective report of body ownership are associated with the cortical thickness in the somatosensory regions, the temporo-parietal junction, the intraparietal areas, and the occipitotemporal cortex, while the proprioceptive drift is linked to the premotor area and the anterior cingulate cortex. These results are in line with functional neuroimaging studies indicating that these areas are indeed involved in processes such as cognitive-affective perspective taking, visual processing of the body, and the experience of body ownership and bodily awareness. Consequently, these individual differences in the sensation of body ownership are pronounced in both functional and structural differences.


Assuntos
Imagem Corporal/psicologia , Ilusões/fisiologia , Individualidade , Córtex Motor/anatomia & histologia , Córtex Motor/fisiologia , Propriedade , Sensação/fisiologia , Adulto , Feminino , Humanos , Masculino , Córtex Somatossensorial/fisiologia , Percepção Visual/fisiologia , Adulto Jovem
9.
Sci Rep ; 11(1): 16653, 2021 08 17.
Artigo em Inglês | MEDLINE | ID: mdl-34404855

RESUMO

Schizotypal personality traits correlate with psychopathology and impaired functional outcome. Yet advantageous aspects of positive schizotypy may exist which could promote resilience and creativity, and several studies have identified a high positive but low negative schizotypy group with some signs of adaptation. The aim of our study was to clarify whether such individuals demonstrate only traits associated with well-being, or they also have traits that predict impairment. Participants (N = 643 students, 71.5% female) completed measures of schizotypy, resilience, self-esteem, self-concept clarity, and absorption. We identified four clusters: an overall low schizotypy, an overall high schizotypy, a disorganised-interpersonal schizotypy and a positive schizotypy cluster. The overall high schizotypy cluster seemed to be the most vulnerable as it was the least resilient and showed widespread maladaptation, whereas the high positive schizotypy cluster had intact self-esteem and high resilience and its elevated absorption may hold the promise for adaptive outcomes such as creativity and positive spirituality. However, the high positive schizotypy cluster lacked self-concept clarity. The results suggest that individuals showing high positive and low negative schizotypy demonstrate features promoting mental well-being to an extent that is higher than in all the other clusters, while their self-concept impairment is similar to that observed in the high and the disorganised-interpersonal schizotypy clusters. Better understanding of these factors could be informative for prevention and treatment of psychosis-spectrum disorders.


Assuntos
Transtorno da Personalidade Esquizotípica/psicologia , Adaptação Psicológica , Adulto , Criatividade , Feminino , Humanos , Masculino , Resiliência Psicológica , Transtorno da Personalidade Esquizotípica/diagnóstico , Transtorno da Personalidade Esquizotípica/epidemiologia , Autoimagem , Adulto Jovem
10.
Front Psychol ; 12: 613074, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33716876

RESUMO

Background: This study aimed to examine magical ideation and absorption traits across non-clinical and clinical groups to determine their potential adaptive and maladaptive functions. Method: We enrolled 760 healthy participants from neighboring communities (female = 53.2%). Moreover, we recruited 318 patients (female = 66.5%), which included 25, 183, and 110 patients with schizophrenia spectrum disorders, anxiety disorders, and mood disorders, respectively. Potentially adaptive and maladaptive sociocognitive functions were measured to determine the role of magical ideation and self-absorption in patients with psychiatric disorders. Results: The degree of magical ideation and absorption gradually increased in the following order: anxiety disorders, mood disorders, and schizophrenia spectrum disorders. Furthermore, enhanced self-absorption-related enhanced consciousness traits were essential indicators of the presence of self-integration weakness in patients with schizophrenia spectrum disorders. Conclusion: Magical ideation and psychological absorption may be considered as mental model construction functions, which result in both gains and handicaps in social adaptation.

11.
Psychiatr Hung ; 34(1): 19-33, 2019.
Artigo em Húngaro | MEDLINE | ID: mdl-31074420

RESUMO

INTRODUCTION: Empirical research in defense mechanisms - a concept that stem from the work of Sigmund and Anna Freud and gave rise to a number of thematic approaches - dates back to the mid-20th century. From the psychometric measure instruments developed since that time, the present investigation was aimed to assess the short form of Defense Style Questionnaire that can be efficiently applied in clinical practice and that was supposed to be used as the sixth diagnostic factor of the new version of DSM. A multi-level validity analysis of DSQ-40 was carried out. METHODS: We applied trait assessing measures for anxiety, avoidant behavior, schizotypal traits and personality disorder diagnostic measures developed for DSM-5. To evaluate discriminant validity we applied instruments that assess the stability of self-esteem and the state of self and that can measure the clarity of self-representations. 670 healthy university students volunteered to participate in the investigation. RESULTS: Based on the applied questionnaires, it was revealed that its inner consistency and validity measures are adequate. Its factors that discriminate neurotic and immature defense styles can be applied to identify persons inclined to use either adaptive or maladaptive defense mechanisms. Our findings correspond to other international research results. CONCLUSION: Our results attest that DSQ-40 is a reliable instrument to assess defense style.


Assuntos
Mecanismos de Defesa , Transtornos da Personalidade , Humanos , Transtornos da Personalidade/diagnóstico , Psicometria , Reprodutibilidade dos Testes , Inquéritos e Questionários
12.
Psychiatry Res ; 271: 178-186, 2019 01.
Artigo em Inglês | MEDLINE | ID: mdl-30481696

RESUMO

This is a cross-sectional nonclinical sample study to examine the different levels of the Ipsiety Disturbance Model (IDM) for schizophrenia spectrum disorders (introduced by Sass and Parnas, 2003). Three faces of schizotypy were studied: diminished self-presence, hyper-reflexivity, and distortion in experience of own self and another person's self-discrimination. A sample of college students (N = 1312) was provided a questionnaire packet that contained the Schizotypy Personality Questionnaire Brief-Revisited (SPQ-BR), the Self-Concept Clarity Sale, the Tellegen Absorption Scale, and Interpersonal Reactivity Index measures. Results: higher absorption capabilities predict higher scores on both the SPQ-BR cognitive and SPQ-BR disorganization factors. High scores in cognitive empathy predicted a low score on both SPQ-BR cognitive and SPQ-BR interpersonal scores. In contrast, higher affective empathy predicted high scores on the SPQ-BR interpersonal factor. The deficiency in self-concept clarity predicted an elevated score on the SPQ-BR cognitive, interpersonal, and disorganization schizotypy symptoms. We argue that a lack of self-concept clarity manifested in both the hyperreflexivity level (measured by absorption) and the metallization level (measured by empathy). We argue that the IDM is a reliable way to interpret functioning with different levels of schizotypy.


Assuntos
Inventário de Personalidade/normas , Escalas de Graduação Psiquiátrica/normas , Psicologia do Esquizofrênico , Transtorno da Personalidade Esquizotípica/psicologia , Estudantes/psicologia , Adulto , Cognição , Estudos Transversais , Empatia , Feminino , Humanos , Masculino , Personalidade , Reprodutibilidade dos Testes , Esquizofrenia , Autoimagem , Isolamento Social/psicologia , Inquéritos e Questionários , Adulto Jovem
13.
Psychiatr Hung ; 33(3): 205-221, 2018.
Artigo em Húngaro | MEDLINE | ID: mdl-30426928

RESUMO

INTRODUCTION: The purpose of the Schizotypy Personality Questionnaire - Brief Revised (SPQ-BR) is to help the diagnosis of schizotypial personality disorders within the framework of the DSM-5 and identification of people with an increased vulnerability towards schizophrenia related symptoms. The aim of our current study is twofold; validation of the SPQ-BR's Hungarian adaptation and investigating it's latent structure. METHODS: The sample consisted of 1702 Hungarian university students and university graduated persons. Exploratory factor analytic procedures were performed, cross-validating their results by the use if confirmatory factor analysis. RESULTS: The results suggested that the Hungarian SPQ-BR is best represented by a model of the hierarchical structure, reflected by seven first order factors, and two higher order dimensions of positive and negative symptoms. On lower order factors males were shown significantly greater constricted affects, and proneness to eccentric behaviors and unusual perceptions, while females were characterized by higher magical thinking, next to stronger social anxieties. Gender differences in the Ideas of references - Suspicion and odd speech scales were found to be non-significant. Concerning it''s validity with other scales we found that magical thinking and unusual perceptions from the positive symptoms significantly positively correlated with the magical ideation (MI), anxiousness (ASI), and self-concept clarity (SCCS) scales, next to a negative correlation between unusual perceptions and the self-esteem (RSES) scale. Among the negative symptoms the No close friends-Constricted affect and the Ideas of references - Suspicion subscales showed significant negative linear associations with the ASI, SCCS scales. CONCLUSION: The Hungarian version of the SPQ-BR showed adequate psychometrical properties, it was found to be reliable.


Assuntos
Psicometria , Transtorno da Personalidade Esquizotípica , Feminino , Humanos , Hungria , Masculino , Personalidade , Reprodutibilidade dos Testes , Inquéritos e Questionários
14.
Psychiatr Hung ; 33(3): 270-281, 2018.
Artigo em Húngaro | MEDLINE | ID: mdl-30426933

RESUMO

INTRODUCTION: The recent Diagnostic and Statistical Manual of Mental Disorders (DSM-5) provided a dimensional model of personality disorders grounded on the empirical validated concept of maladaptive personality traits. Accordingly, based on this model, the Personality Inventory for DSM-5 Brief Form (PID-5-BF) enables the identification of maladaptive personality traits in 5 dimensions: Negative Affect, Detachment, Antagonism, Disinhibition and Psychoticism. Former studies showed, that this self-report measure can reliably predict the likelihood of the development of personality disorders. AIM: We aimed to develop the Hungarian version of the PID-5-BF and to verify its construct-, concurrent-, predictive-, and discriminative validity. METHOD: Based on the results of former studies regarding PID-5-BF, we asked 379 participants to fill out several selfreport measures. Besides PID-5-BF, the Bipolar Rating Scale for the Big Five Personality, the Unconventionality subscale from the Openness scale of the HEXACO model and the Interpersonal Problems-Personality Disorders-25 were also administered. RESULTS: According to the original 5 factor version, the fit of our model was acceptable (CFI = 0,868; RMSEA = 0,061 [90% CI = 0,055 - 0,068]; Cronbach-alpha = 0,61-0,79). In our view, the results vindicate the reliability and validity of the Hungarian PID-5-BF. CONCLUSIONS: According to former studies along with our recent findings, the PID-5-BF can be seen as an effective and reliable self-report scale for clinical studies and at the same time, it may be useful for the psychiatric diagnostic process, mainly in the case of personality disorders. With more clinical data and knowledge, this inventory could be useful for psychiatrists and clinical psychologists in planning of clinical treatment.


Assuntos
Transtornos da Personalidade , Inventário de Personalidade , Personalidade , Manual Diagnóstico e Estatístico de Transtornos Mentais , Humanos , Hungria , Reprodutibilidade dos Testes , Autorrelato
15.
Orv Hetil ; 159(36): 1455-1464, 2018 Sep.
Artigo em Húngaro | MEDLINE | ID: mdl-30175604

RESUMO

The present study aims at overviewing the different stages of the education of medical psychology in Hungary. In the perspective of the achievements of cognitive and affective neuroscience as well as developmental psychology, we intend to define the roots of doctor-patient relationship, certain determining factors of diagnosis forming and therapy efficiency as well as the essential components of empathy. We attest to the fact that the current psychosomatic medicine with its evidence-based achievements is a valid component and constitutive pillar of everyday medical care. The integrated university level instruction of medical psychology and behavioral sciences aims at consolidating this perspective. We also emphasize that the ill body hinders adequate psychological functioning and mental disorders provide risk factors concerning somatic illnesses. Through spreading health psychology perspective, we support the concept that in everyday medical care, health protection and the development of health conscious behavior relies on responsible, informed and committed decision-making patients as well as on similarly educated extended medical care teams. Orv Hetil. 2018; 159(36): 1455-1464.


Assuntos
Transtornos Mentais/terapia , Assistência Centrada no Paciente/organização & administração , Psicologia Médica/organização & administração , Ciências do Comportamento/organização & administração , Humanos , Hungria , Relações Médico-Paciente
16.
Psychol Rep ; 121(6): 996-1012, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29298579

RESUMO

The Dark Triad is a collection of socially aversive personality traits, namely subclinical psychopathy, Machiavellianism, and subclinical narcissism. These deviant traits, however, contribute to the success of individuals with dark personality traits. Therefore, Dark Triad traits can be conceived as pseudopathologies. Schizotypal traits have also been studies from the perspective of behavioral adaptations. In this study, we investigated whether schizotypal traits were associated with the Dark Triad traits and how schizotypal symptoms can be considered as parts of dark interpersonal strategies that contribute to the individual success of people with dark personality traits. A sample of 277 university students (198 females and 79 males; Mage = 20.64; SDage = 2.15) were recruited to fill out the Short Dark Triad and the Schizotypal Personality Questionnaire-Brief Revised. Statistical analyses revealed that Machiavellianism was positively associated with restricted emotional and social life. Narcissism was negatively associated with interpersonal problems. Psychopathy was positively associated with distorted perceptions/cognitions and disorganization. Results of the study are discussed within a behavioral ecology framework. This perspective emphasizes the adaptive values connected to schizotypal personality traits. We further discuss how these adaptive traits fit into strategies of individuals with Dark Triad traits, and how these schizotypal traits might restrict or further promote their individual success.


Assuntos
Maquiavelismo , Narcisismo , Personalidade/fisiologia , Adolescente , Adulto , Emoções/fisiologia , Feminino , Humanos , Masculino , Psicometria , Inquéritos e Questionários , Adulto Jovem
17.
Cogn Process ; 18(4): 349-357, 2017 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-28780698

RESUMO

The aim of the present study was to compare junior and senior healthy participants for their multimodal integration capability. The instrument used for the investigation was the rubber hand illusion (RHI) where synchronous and asynchronous multimodal stimulation were applied. The study focused on assessing the rate of integration for visuo-tactile and visuo-proprioceptive stimuli. METHODS: From a large sample of right-handed volunteers, 50 senior employees (containing younger and middle age adults) and 51 senior retired (senior adults) participants were recruited. RESULTS: The between-subject analyses revealed that individuals both the junior and the senior participants responded to induction of RHI with vivid ownership and disownership experiences and a higher mislocalization error in the synchronous condition. However, the between-group analysis showed that participants in the senior group reported less vivid ownership and less vivid total RHI experiences scores compared to members of the junior group, but no mislocalization error differences were found between the groups. CONCLUSION: The results indicated that when visuo-tactile stimuli synchronously presented, the gain in multisensory integration decreased in seniors group. In contrast, in the case of visuo-proprioceptive synchronous presentation, the efficiency of multisensory integration remained unchanged across the lifespan.


Assuntos
Imagem Corporal , Mãos , Ilusões/fisiologia , Propriocepção/fisiologia , Percepção do Tato/fisiologia , Percepção Visual/fisiologia , Adulto , Fatores Etários , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem
18.
Behav Brain Res ; 332: 75-83, 2017 08 14.
Artigo em Inglês | MEDLINE | ID: mdl-28577920

RESUMO

The MAM-E17 model is one of the most accepted schizophrenia rat models, which follows the neurodevelopmental theory of the disease. While symptoms of MAM-E17 rats were studied extensively, their examinations were usually restricted to adulthood and in a few cases to prepuberty. It is well known, however, that schizophrenia symptoms often start at puberty or early adulthood. Therefore the purpose of this study was to investigate the behavioral characteristics of MAM-E17 rats in various tests throughout three different age-periods, namely in prepuberty, late puberty and adulthood. In open field test, MAM-E17 rats displayed increased locomotor activity, elevated sniffing frequency and, as tendency, enhanced rearing activity. The elevated activity turned up in late puberty and remained there in adulthood, too. There was also a deficient prepulse inhibition (PPI) of startle response in late puberty and adulthood, but not before puberty. In rotarod task, MAM-treated rats performed better than control rats. The enhanced performance on rotarod was only present in late puberty and adulthood. In elevated plus maze test MAM-treated rats displayed diminished anxiety mostly in prepuberty. Histological analysis revealed reduced volume and cell disarray in the dorsal hippocampus. This is the first comprehensive study about symptoms of MAM-E17 rats manifested in behavioral tests carried out in prepuberty, late puberty and adulthood. Results display the age-dependent appearance of schizophrenia symptoms in the same rats. The present findings provide basic information to accomplish the schizophrenia related animal research, as well as can also confer further data to develop preventive treatment for human patients.


Assuntos
Envelhecimento/psicologia , Modelos Animais de Doenças , Esquizofrenia , Envelhecimento/patologia , Animais , Ansiedade , Comportamento Exploratório , Feminino , Hipocampo/patologia , Masculino , Acetato de Metilazoximetanol , Atividade Motora , Gravidez , Efeitos Tardios da Exposição Pré-Natal , Inibição Pré-Pulso , Ratos Wistar , Teste de Desempenho do Rota-Rod , Esquizofrenia/patologia , Psicologia do Esquizofrênico
19.
Psychiatr Hung ; 32(1): 54-64, 2017.
Artigo em Húngaro | MEDLINE | ID: mdl-28424380

RESUMO

Nowadays, both in the clinical population, and in general communities, we tend to encounter an increasing number of personality disorder patients, whose social adjustment, partnerships and efficient life management is made difficult by the disorder. The ideas of borderline personality disorder patients, who fluctuate between farfetched expectations and fears of their selves being demolished, schizoid patients, who close their selves in their own alienating prison, avoidant patients, who try to escape difficulties, which would enhance their self-esteem, OCD patients, who build their own mythic superstitious world, and antisocial patients who tend to ignore and aggressively override others' interests are all important in the development of cultures with insecure identities. Taking into consideration the symptoms enlisted in the diagnostic system of DSM-5, it is the task of experts of cultural anthropology, psychology, psychopathology and cognitive neuroscience to explore the referring ways of personality development, relationships and of conflict management. Notwithstanding, avoiding the psychopathological terminology, rather pointing at population characteristics, we need to identify personal functionings of the general features of perception, cognition and world views, which in the long run, may modify personal developmental possibilities, individual approaches to information technology, and emotional, family or professional motivations. Based on the respective literature and clinical experience, below we intend to explore the different aspects of schizotypy, which contribute to the formation of schizoid personality disorder. We analyze the interrelations of avoiding relationships and empathy toward relationship building.


Assuntos
Transtorno da Personalidade Esquizotípica , Cognição , Manual Diagnóstico e Estatístico de Transtornos Mentais , Humanos , Transtorno da Personalidade Esquizotípica/diagnóstico , Transtorno da Personalidade Esquizotípica/psicologia
20.
Parkinsons Dis ; 2017: 6434689, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28293444

RESUMO

Introduction. In the genesis of Parkinson's disease (PD) clinical phenomenology the exact nature of the association between bradykinesia and affective variables is unclear. In the present study, we analyzed the gait characteristics and level of depression in PD and healthy volunteers. Methods. Patients with PD (n = 48) and healthy controls (n = 52) were recruited for the present study. Walking speed, stride length, and cadence were compared between groups while participants completed a goal-directed locomotion task under visually controlled (VC) and visually noncontrolled conditions (VnC). Results. Significantly higher depression scores were found in PD comparing to healthy control groups. In PD, depression was associated with gait components in the VC wherein the place of the target was visible. In contrast, in healthy subjects the depression was associated with gait components in VnC wherein the location and image of the target were memorized and recalled. In patients with PD and depression, the visually deprived multitask augments the rate of cadence and diminishes stride length, while velocity remains relatively unchanged. The depression associated with gait characteristics as a comorbid affective factor in PD, and that impairs the coherence of gait pattern. Conclusion. The relationship between depression and gait parameters appears to indicate that PD not only is a neurological disease but also incorporates affective disturbances that associate with the regulation of gait characteristics.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...