1.
Ann N Y Acad Sci
; 973: 181-5, 2002 Nov.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12485857
RESUMO
In the absence of phosphorylated Gab2, immature B cells are unable to maintain a prolonged signal transduction, which is necessary for the transcriptional regulation and activation of the cells. Thus, the lack of Gab2 phosphorylation may drive immature B cells to apoptosis.