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1.
J Cardiovasc Surg (Torino) ; 43(2): 295-7, 2002 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-11887074

RESUMO

A 5-month-old boy who had been operated for esophageal atresia and tracheoesophageal fistula was presented with recurrent life-threatening apneic spells, expiratory stridor and difficulty in feeding. Diagnosis of tracheomalacia was confirmed by bronchoscopy and pericardial flap aortopexy was performed. Pericardial flap aortopexy is a relatively simple procedure with minimal risk to the aorta. Minimal dissection is required and there are no sutures placed in the aortic wall, thus avoiding the risk of tears.


Assuntos
Aorta/cirurgia , Doenças das Cartilagens/cirurgia , Atresia Esofágica/cirurgia , Traqueia/anormalidades , Doenças da Traqueia/cirurgia , Fístula Traqueoesofágica/cirurgia , Fatores Etários , Doenças das Cartilagens/diagnóstico , Atresia Esofágica/complicações , Refluxo Gastroesofágico/cirurgia , Humanos , Recém-Nascido , Imageamento por Ressonância Magnética , Masculino , Pericárdio , Retalhos Cirúrgicos , Doenças da Traqueia/diagnóstico , Estenose Traqueal/diagnóstico , Fístula Traqueoesofágica/complicações , Traqueostomia
2.
Clin Exp Med ; 1(1): 61-6, 2001 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-11467403

RESUMO

Bacterial translocation is thought to be responsible for infectious complications after hemorrhagic shock. The aim of this study was to investigate the effects of pentoxifylline treatment on bacterial translocation in animals subjected to hemorrhagic shock. Thirty-one Wistar albino rats (280-360 g) were divided into three groups: sham (n=10), shock (n=11), and shock-pentoxifylline (n=10). Blood was not withdrawn from sham rats. Shock rats were subjected to 30 min of shock followed by reinfusion of shed blood. Shock/pentoxifylline rats received pentoxifylline after reinfusion of shed blood. After hemorrhage and reinfusion (24 h), the mesenteric lymph nodes, liver, spleen, and blood samples were evaluated using quantitative microbiological techniques, and the numbers of colony-forming units were compared between groups. Cecum was removed to evaluate the bacterial population. Ileum and cecum were examined histologically. The incidence of bacterial translocation was higher in the shocked rats (63%) than in the sham shock rats (10%). Pentoxifylline reduced the incidence of shock-induced bacterial translocation to 0%. Cecal bacterial levels were significantly higher in the shock rats than in the sham and shock/pentoxifylline rats. The histological damage caused by hemorrhagic shock was prevented by pentoxifylline treatment. In conclusion, the hemorrhagic shock triggered translocation of bacteria to the mesenteric lymph nodes, spleen, liver, and blood of rats. Pentoxifylline treatment just after shed blood transfusion significantly attenuated this phenomenon.


Assuntos
Translocação Bacteriana/efeitos dos fármacos , Mucosa Intestinal/patologia , Choque Hemorrágico/fisiopatologia , Animais , Infecções Bacterianas/prevenção & controle , Translocação Bacteriana/fisiologia , Sangue/microbiologia , Transfusão de Sangue Autóloga , Ceco , Citrobacter/isolamento & purificação , Modelos Animais de Doenças , Enterococcus/isolamento & purificação , Escherichia coli/isolamento & purificação , Íleo , Mucosa Intestinal/efeitos dos fármacos , Fígado/microbiologia , Linfonodos/microbiologia , Masculino , Pentoxifilina , Proteus/isolamento & purificação , Ratos , Ratos Wistar , Choque Hemorrágico/patologia , Baço/microbiologia , Staphylococcus/isolamento & purificação , Streptococcus/isolamento & purificação
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