RESUMO
With the aim of investigating the influence of trisomy 21 on the expression of heritable morphological features, we recorded the palmar and plantar dermatoglyphic patterns in 48 children with Down syndrome (DS), in both their parents, and, as a control, in 57 of their siblings. Using the Kendall tau rank correlation test, a considerable parental influence on the frequency of true patterns in the interdigital areas (IDA) III and IV of the palms (P = 0.3%) and soles (P = 1.0% and 3.8%, respectively) is demonstrated for the control siblings. In the children with DS, this influence is discernible as well, although with no statistical significance. A greater number of families may be required to settle the question.
Assuntos
Síndrome de Down/fisiopatologia , Deformidades Congênitas do Pé/fisiopatologia , Deformidades Congênitas da Mão/fisiopatologia , Síndrome de Down/genética , Meio Ambiente , Feminino , Deformidades Congênitas do Pé/genética , Predisposição Genética para Doença , Deformidades Congênitas da Mão/genética , Humanos , Masculino , Núcleo Familiar , Fenótipo , Tamanho da Amostra , Estatística como AssuntoRESUMO
BACKGROUND: Aspergillus abscesses of the kidneys are very rare complications of AIDS which usually have fatal outcome. The 4 patients described in the literature, 2 of whom had bilateral involvement, died due to this opportunistic infection. METHODS: Case report of a 33-year-old patient with AIDS in stage C3 and aspergillus abscesses of the kidney. RESULTS: Successful treatment of bilateral aspergillus abscesses of the kidneys with purely conservative antimycotic measures. This was largely due to stabilization of the immune status by supplementing antiretroviral treatment with the proteinase inhibitor indinavir. CONCLUSIONS: The options now available for improving immune status in AIDS also improve the treatment chances in renal aspergillosis.