RESUMO
A 13-month-old girl developed multiple pruritic, 1- to 7-cm, vegetating and ulcerative masses on the neck, extremities, and trunk after a one-week course of an antibiotic and an expectorant that contained potassium iodide, prescribed for treatment of a respiratory tract infection. Clinical and histopathologic findings were consistent with the diagnosis of iododerma. A thorough search for an underlying disease was negative. On cessation of potassium iodide and administration of oral prednisolone 1 mg/kg/day, a dramatic response was achieved.
Assuntos
Toxidermias/etiologia , Iodeto de Potássio/efeitos adversos , Anti-Inflamatórios/uso terapêutico , Biópsia por Agulha , Diagnóstico Diferencial , Toxidermias/diagnóstico , Toxidermias/tratamento farmacológico , Toxidermias/fisiopatologia , Feminino , Humanos , Lactente , Iodeto de Potássio/uso terapêutico , Prednisolona/uso terapêutico , Infecções Respiratórias/tratamento farmacológico , Pele/patologiaAssuntos
Antineoplásicos/uso terapêutico , Calcitriol/análogos & derivados , Fármacos Dermatológicos/uso terapêutico , Papiloma/tratamento farmacológico , Neoplasias Cutâneas/tratamento farmacológico , Administração Cutânea , Adulto , Antineoplásicos/administração & dosagem , Calcitriol/administração & dosagem , Calcitriol/uso terapêutico , Cálcio/sangue , Fármacos Dermatológicos/administração & dosagem , Feminino , Humanos , Pomadas , Neoplasias Torácicas/tratamento farmacológicoRESUMO
A 10-year-old girl had focal dermal hypoplasia (Goltz syndrome). She showed the characteristic skin manifestations, mental and physical underdevelopment, and facial, dental, skeletal, ophthalmologic, and urinary abnormalities. In addition, she had a horseshoe kidney abnormality.
Assuntos
Anormalidades Múltiplas , Hipoplasia Dérmica Focal , Rim/anormalidades , Criança , Feminino , Hipoplasia Dérmica Focal/patologia , HumanosAssuntos
Psoríase/metabolismo , Pele/química , Substância P/análise , Feminino , Humanos , MasculinoAssuntos
Interferon gama/uso terapêutico , Leishmaniose/terapia , Animais , Antimônio/uso terapêutico , Antiprotozoários/uso terapêutico , Humanos , Leishmania tropica , Leishmaniose/tratamento farmacológico , Meglumina/uso terapêutico , Antimoniato de Meglumina , Compostos Organometálicos/uso terapêutico , Proteínas RecombinantesRESUMO
We describe a patient with localized scleroderma in association with homolateral atrophy of the tongue and marked ipsilateral facial hemiatrophy which was confirmed histologically. CT scan coronal sections of the face showed severe atrophy of the tongue and facial muscles. The EMG studies failed to demonstrate a neurogenic or myogenic process.
