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Nucleic Acids Res ; 47(D1): D1128-D1136, 2019 01 08.
Artigo em Inglês | MEDLINE | ID: mdl-30321383

RESUMO

The Cucurbitaceae family (cucurbit) includes several economically important crops, such as melon, cucumber, watermelon, pumpkin, squash and gourds. During the past several years, genomic and genetic data have been rapidly accumulated for cucurbits. To store, mine, analyze, integrate and disseminate these large-scale datasets and to provide a central portal for the cucurbit research and breeding community, we have developed the Cucurbit Genomics Database (CuGenDB; http://cucurbitgenomics.org) using the Tripal toolkit. The database currently contains all available genome and expressed sequence tag (EST) sequences, genetic maps, and transcriptome profiles for cucurbit species, as well as sequence annotations, biochemical pathways and comparative genomic analysis results such as synteny blocks and homologous gene pairs between different cucurbit species. A set of analysis and visualization tools and user-friendly query interfaces have been implemented in the database to facilitate the usage of these large-scale data by the community. In particular, two new tools have been developed in the database, a 'SyntenyViewer' to view genome synteny between different cucurbit species and an 'RNA-Seq' module to analyze and visualize gene expression profiles. Both tools have been packed as Tripal extension modules that can be adopted in other genomics databases developed using the Tripal system.


Assuntos
Biologia Computacional/métodos , Produtos Agrícolas/genética , Cucurbita/genética , Bases de Dados Genéticas , Genoma de Planta/genética , Genômica/métodos , Biologia Computacional/estatística & dados numéricos , Produtos Agrícolas/classificação , Produtos Agrícolas/crescimento & desenvolvimento , Cucurbita/classificação , Cucurbita/crescimento & desenvolvimento , Etiquetas de Sequências Expressas , Perfilação da Expressão Gênica/métodos , Armazenamento e Recuperação da Informação/métodos , Internet , Especificidade da Espécie , Sintenia
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