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Physiol Res ; 57(2): 237-245, 2008.
Artigo em Inglês | MEDLINE | ID: mdl-17552880

RESUMO

Experimental and epidemiological studies suggest that calcium intake is inversely related to weight gain. Calcium of dairy origin has been shown to be more effective in promoting weight loss. However, clinical studies yielded controversial results concerning the role of calcium intake in weight change. The aim of this study was to ascertain whether the addition of calcium can affect the outcome of 3-week weight management (WM) with a hypocaloric diet characterized by a decreased calcium intake. Overweight/ obese women (n=67; BMI 32.2+/-4.1 kg/m(2); age 49.1+/-12.1 years) underwent a 4-week comprehensive WM program. WM included a 7 MJ/day diet resulting in a stable weight during the first week and a 4.5 MJ/day diet with mean daily calcium intake 350 mg during the second to fourth week. Participants were divided into three age- and BMI-matched groups who received placebo or calcium (500 mg/day). Calcium was administered either as carbonate or calcium of dairy origin (Lactoval). There was no significant difference in weight loss in response to WM between the placebo-treated and calcium-treated groups. However, addition of calcium to the diet resulted in a lower hunger score in the Eating Inventory as well as a decrease in plasma resistin levels. Body composition measured by bioimpedance demonstrated that added calcium leads to preservation of fat-free mass. Nevertheless, a greater loss of fat-free mass in the placebo group might be partly due to a greater loss of water.


Assuntos
Cálcio da Dieta/administração & dosagem , Suplementos Nutricionais , Obesidade/tratamento farmacológico , Redução de Peso/fisiologia , Adulto , Análise de Variância , Dieta Redutora , Feminino , Humanos , Fome/efeitos dos fármacos , Análise por Pareamento , Pessoa de Meia-Idade , Estatísticas não Paramétricas , Fatores de Tempo , Resultado do Tratamento , Redução de Peso/efeitos dos fármacos
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