RESUMO
A 24-hour electron microscopic examination of neuronal and capillary ultrastructure in sensorimotor complex was performed after whole-body neutron irradiation of mature rats in the dose of 10 Gy. The results suggest that postradiation neuronal changes, observed for 6 hours after irradiation, are mainly caused by direct effect of ionizing radiation. At later terms this process is influenced by blood capillary lesions. The effect of neutron irradiation at the ultrastructural level is similar to that of rarely ionizing radiation.
Assuntos
Córtex Cerebral/ultraestrutura , Nêutrons , Lesões Experimentais por Radiação/patologia , Doença Aguda , Animais , Capilares/efeitos da radiação , Capilares/ultraestrutura , Córtex Cerebral/irrigação sanguínea , Masculino , Dilatação Mitocondrial/efeitos da radiação , Ratos , Ratos Endogâmicos , Fatores de Tempo , Irradiação Corporal TotalRESUMO
At early times (15 min to 6 h) after whole-body gamma-neutron irradiation of mature rats with a dose of 10 Gy reactive changes occur in neurons of the sensimotor cerebral cortex which can be interpreted as a manifestation of the enhancement of functional and metabolic activity of nerve cells followed by inhibition thereof.