Roles of attitudes and injunctive norms in decisional conflict and disclosure following receipt of genome sequencing results.

RATIONALE: Individuals who choose to obtain genetic information may learn that their genetic profile confers health risks to themselves or offspring. Individuals may react more negatively to this information when personal attitudes, perceived norms, and/or the decision to receive results conflict with one another. OBJECTIVE: We predicted that holding more negative attitudes (personal evaluations) or injunctive norms (perceptions of others' approval) toward obtaining genetic test results would prospectively predict greater conflict about the decision to undergo sequencing and less disclosure of sequencing results to family members. We also expected attitudes and norms to interact, such that attitudes would be negatively associated with decisional conflict and positively associated with disclosure when injunctive norms were positive, but weakly associated with outcomes when injunctive norms were negative. METHOD: Participants (N=312) were enrolled in a genomic sequencing trial focused on identifying carrier genetic variants, reflecting a variant that might affect their biological children's or grandchildren's health. Participants reported attitudes and injunctive norms, underwent sequencing, and later received results indicating carrier status for at least one variant. Decisional conflict was assessed at immediate post-test, and 1- and 6-month follow-ups. Disclosure of results to children and siblings were assessed at 1 and 6 months. RESULTS: In structural equation models with covariates, attitudes were negatively associated with post-test and 1-month decisional conflict. Injunctive norms were negatively associated with decisional conflict at 1 and 6 months and positively associated with disclosure to children and siblings at 1 month. The significant attitudes by injunctive norms interaction predicting post-test decisional conflict supported lower decisional conflict when attitudes, norms, and the decision to receive results were all aligned. Exploratory analyses supported indirect effects of attitudes and norms on 6-month sibling disclosure via 1- month decisional conflict. CONCLUSION: Results support roles of psychosocial factors in decisional conflict and disclosure after receiving sequencing results.

Are college students' perceptions of social network drinking accurate?: Examining the validity of the Important People Instrument.

A growing body of research has examined self-reported measures of social network alcohol use, such as the Important People Instrument (IPI), among college students. However, it remains unknown whether IPI judgments of friends' alcohol use are accurate. We hypothesized that judgments of friends' drinking status (e.g., heavy drinker) and maximum drinks per day would primarily reflect friends' self-report (accuracy), rather than projection of participants' self-report (assumed similarity) or a systematic tendency to under- or overestimate behavior (directional bias). We also expected that accuracy would be stronger when participants were women, had more contact with friends, or drank less each week or when friends drank less each week. In all, 654 randomly selected, 1st-year students indicated their 5 closest friends in their class, yielding 111 friendship dyads. Participants judged each friend's drinking status and maximum drinks per day and rated these items for themselves. Gender, frequency of contact, and typical drinks per week were assessed. Results indicated that judgments of drinking status and maximum drinks per day were highly accurate. Accuracy effects were consistently stronger than was assumed similarity; directional bias was nonsignificant. Accuracy did not depend on gender or participants' weekly consumption but was stronger for both outcomes when contact was more frequent and, for maximum drinks per day, when friends' weekly consumption was relatively low. Results support validity of the IPI for assessing social network alcohol use among students. Given that perceptions are accurate, research is needed on intervention strategies that facilitate management of risky peers. (PsycINFO Database Record (c) 2020 APA, all rights reserved).