1.
Org Lett
; 14(6): 1366-9, 2012 Mar 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-22364480
RESUMO
The thermal reaction of 1,4-bisallenes with the aid of Cu salt/amine significantly suppressed the formal [3,3] sigmatropic rearrangement resulting in the highly selective formation of the bicyclo[4.2.0]octadiene framework. This reaction could be applied to the one-pot synthesis of bicyclo[4.2.0]octadienes from 1,5-hexadiynes via the Crabbé homologation.