RESUMO
BACKGROUND: Comparative clinical studies play a major role in evaluating the relative efficacy of commercially available manual toothbrushes to improve periodontal health. A manual toothbrush with angled, CrissCross® bristles has been shown to offer significant benefits relative to other toothbrushes. This study assessed whether the benefits could also be observed in real-world, normal use conditions in a large population. MATERIALS AND METHODS: Generally, healthy adult participants were recruited from 24 dental institutions across India and given the manual toothbrush with angled bristles to use. Their periodontal health was assessed subjectively by dentists, using response categories, at the start of the study (baseline) and after 12 weeks of normal use. Participants themselves were also questioned. Data analyses were descriptive. RESULTS: A total of 2157 participants took part in this multicenter study. At 12 weeks, oral hygiene status and gingival health were categorized as good to excellent in at least 85% of participants compared with 61%-62% at baseline, and no staining was found in 40% of participants compared with 30% at baseline. Oral health improvements were seen in 75% of participants. Most participants reported their brushing experience as giving good-to-excellent satisfaction (85%), improved brushing (82%), and a cleaner mouth (81%) and said they would recommend the brush (90%). CONCLUSIONS: In this uncontrolled real-world study, improvements were observed in oral health and hygiene following the use of the manual toothbrush with CrissCross bristles over 12 weeks. The results lend support to earlier findings of comparative clinical studies that demonstrated the beneficial effects of this toothbrush for periodontal health.
RESUMO
UNLABELLED: To determine and compare the clinical performance of formulations containing 7.5% calcium sodium phosphosilicate (NovaMin), 5% potassium nitrate, and 0.4% stannous fluoride for the management of dentin hypersensitivity. METHODS: This was a single-center, randomized, double-blind, parallel-group design with a duration of 12 weeks. The study included a total of 120 subjects and measured sensitivity to cold water and air blast by the use of a visual analogue scale. Measurements were taken at baseline, two, four, and 12 weeks. RESULTS: All three products significantly reduced sensitivity versus baseline at each time point, although the calcium sodium phosphosilicate (NovaMin) dentifrice reduced sensitivity significantly more than the others at the two- and four-week time points. At the two-week time point, for air and water, respectively, the dentifrice containing NovaMin reduced sensitivity 45% and 49%, the stannous fluoride gel 30% and 26%, and the potassium nitrate dentifrice 35% and 34%. At the 12-week time point, the dentifrice containing NovaMin reduced sensitivity 87% and 91%, stannous fluoride gel 87% and 85%, and potassium nitrate dentifrice 84% and 79%. CONCLUSION: In this study, all three products were effective. Compared to the potassium nitrate and stannous fluoride formulations, the dentifrice containing NovaMin provided more substantial and significant improvements at the early time points.
