[IMMUNOMORPHOLOGICAL FEATURES OF THE PLACENTA IN MULTIPLE PREGNANCIES].

Placentas clinical and immunological research in women with multiple pregnancy, noted the presence of morphological and functional, immunopathologic changes of varying severity. It is proved that in women with miscarriage at the level of multiple pregnancy placental insufficiency depends on the blood supply to the placenta and the nature of the inflammatory manifestations. The morphological pattern of placental disorders in miscarriage was revealed that the morphological features of placental insufficiency in non-infectious factors of miscarriage are early changes in the vessels of the decidua in a spasm, obliteration of the lumen of the spiral arteries, a decrease of vascular villous tree, reducing the amount of chorionic epithelium and peripheral trophoblast, increased maternal and fetal deposits fibrinoid. Thanks to the research will be possible to form a clear vision that would allow on the basis of public spending immunomorfological features pathogenetically substantiated therapy prenatal complications arising from multiple pregnancies.

[PROBLEMS OF NEWBORN NEONATAL ADAPTATION FROM A TWINS].

The clinical analysis of multiple pregnancies. The features of neonatal adaptation process in 96 twins, depending on the type of zygosity. It is proved that the adaptation of the newborn with multiple pregnancy depends on the type of placentation. It is found that monozygotic twins is a risk factor syndromes disadaptation. Children from monozygotic twins compared with dizygotic twins have a higher frequency of the syndrome of respiratory disorders, and more prone to jaundice, hemorrhagic syndrome, violation gemolikvorodinamics II and III degrees. The physical development of the twins also determined by the type zygosity. In the group of monozygotic twins are more common heavier versions of intrauterine growth retardation - hypoplastic and dysplastic. The high frequency of asphyxia on the background of immaturity that leads to the development disadaptation syndromes in these children, the most common of which are hypoxic-ischemic CNS disorders, thermoregulation, jaundice and gastrointestinal reactions. Detection disorders of blood coagulation and glucose metabolism certainly play a negative role in the development of adaptation of these newborns. zygosity type must be determined at the time of pregnancy to produce medical tactics and prognosis.