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1.
JMIR Res Protoc ; 11(9): e41152, 2022 Sep 13.
Artigo em Inglês | MEDLINE | ID: mdl-36099009

RESUMO

BACKGROUND: Spinal cord injury (SCI) constitutes a major sociomedical problem, impacting approximately 0.32-0.64 million people each year worldwide; particularly, it impacts young individuals, causing long-term, often irreversible disability. While effective rehabilitation of patients with SCI remains a significant challenge, novel neural engineering technologies have emerged to target and promote dormant neuroplasticity in the central nervous system. OBJECTIVE: This study aims to develop, pilot test, and optimize a platform based on multiple immersive man-machine interfaces offering rich feedback, including (1) visual motor imagery training under high-density electroencephalographic recording, (2) mountable robotic arms controlled with a wireless brain-computer interface (BCI), (3) a body-machine interface (BMI) consisting of wearable robotics jacket and gloves in combination with a serious game (SG) application, and (4) an augmented reality module. The platform will be used to validate a self-paced neurorehabilitation intervention and to study cortical activity in chronic complete and incomplete SCI at the cervical spine. METHODS: A 3-phase pilot study (clinical trial) was designed to evaluate the NeuroSuitUp platform, including patients with chronic cervical SCI with complete and incomplete injury aged over 14 years and age-/sex-matched healthy participants. Outcome measures include BCI control and performance in the BMI-SG module, as well as improvement of functional independence, while also monitoring neuropsychological parameters such as kinesthetic imagery, motivation, self-esteem, depression and anxiety, mental effort, discomfort, and perception of robotics. Participant enrollment into the main clinical trial is estimated to begin in January 2023 and end by December 2023. RESULTS: A preliminary analysis of collected data during pilot testing of BMI-SG by healthy participants showed that the platform was easy to use, caused no discomfort, and the robotics were perceived positively by the participants. Analysis of results from the main clinical trial will begin as recruitment progresses and findings from the complete analysis of results are expected in early 2024. CONCLUSIONS: Chronic SCI is characterized by irreversible disability impacting functional independence. NeuroSuitUp could provide a valuable complementary platform for training in immersive rehabilitation methods to promote dormant neural plasticity. TRIAL REGISTRATION: ClinicalTrials.gov NCT05465486; https://clinicaltrials.gov/ct2/show/NCT05465486. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/41152.

2.
Micromachines (Basel) ; 12(8)2021 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-34442584

RESUMO

A flutter-type, nonlinear piezoelectric energy harvester was tested in various combinations of aerodynamic and harmonic base excitation to study its power output and efficiency. The commercial polyvinylidene fluoride film transducer LDT1-028K was used in 33 excitation mode. The aerodynamic excitation was created by a centrifugal fan and the base excitation by a cone speaker. The excitations were produced by varying independently the mean airflow velocity and the frequency of base vibration. A capacitive load was used to store the harvested energy. A line laser was employed along with long exposure photography and high-speed video, for the visualization of the piezo film's mode shapes and the measurement of maximum tip deflection. The harvested power was mapped along with the maximum tip deflection of the piezo-film, and a process of optimally combining the two excitation sources for maximum power harvesting is demonstrated. The energy conversion efficiency is defined by means of electrical power output divided by the elastic strain energy rate of change during oscillations. The efficiency was mapped and correlated with resonance conditions and results from other studies. It was observed that the conversion efficiency is related to the phase difference between excitation and response and tends to decrease as the excitation frequency rises.

3.
J Acoust Soc Am ; 146(2): 1438, 2019 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-31472588

RESUMO

Current hybrid computational aeroacoustic methodologies for broadband noise prediction rely on large eddy simulation (LES) for noise source computation, and integral methods for noise propagation. In this paper, LES of a benchmark controlled-diffusion airfoil was conducted, utilizing the rotation rate based Smagorinsky model (RoSM). The RoSM is seen to provide flow results of equal or improved accuracy as compared to the dynamic Smagorinsky model, with 35% less computational cost, with computational benefits of the RoSM increasing with mesh size. Current integral methods for noise propagation, including Formulation 1A of Farassat, require numerical differentiation of highly turbulent input flow data coming from LES, introducing numerical inaccuracies. Here, Formulation 1 of Farassat is modified to entirely avoid the numerical differentiation of flow field data. The ability of the methodology for broadband noise prediction is demonstrated, with the prediction at high frequencies being considerably closer to experimental data than Formulation 1A. For low discrete frequency noise prediction, Formulation 1A is still recommended. The use of two innovative approaches in conjunction for broadband noise prediction is seen to be efficient and easy to implement, without compromising on accuracy.

4.
Sensors (Basel) ; 15(9): 24318-42, 2015 Sep 22.
Artigo em Inglês | MEDLINE | ID: mdl-26402682

RESUMO

Measurement of gas density and viscosity was conducted using a micro-cantilever beam. In parallel, the validity of the proposed modeling approach was evaluated. This study also aimed to widen the database of the gases on which the model development of the micro-cantilever beams is based. The density and viscosity of gases are orders of magnitude lower than liquids. For this reason, the use of a very sensitive sensor is essential. In this study, a micro-cantilever beam from the field of atomic force microscopy was used. Although the current cantilever was designed to work with thermal activation, in the current investigation, it was activated with an electromagnetic force. The deflection of the cantilever beam was detected by an integrated piezo-resistive sensor. Six pure gases and sixteen mixtures of them in ambient conditions were investigated. The outcome of the investigation showed that the current cantilever beam had a sensitivity of 240 Hz/(kg/m³), while the accuracy of the determined gas density and viscosity in ambient conditions reached ±1.5% and ±2.0%, respectively.

5.
IEEE J Biomed Health Inform ; 19(5): 1707-17, 2015 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25265618

RESUMO

This paper presents a novel method for tracking the position of a medical instrument's tip. The system is based on phase locking a high frequency signal transmitted from the medical instrument's tip to a reference signal. Displacement measurement is established having the loop open, in order to get a low frequency voltage representing the medical instrument's movement; therefore, positioning is established by means of conventional measuring techniques. The voltage-controlled oscillator stage of the phase-locked loop (PLL), combined to an appropriate antenna, comprises the associated transmitter located inside the medical instrument tip. All the other low frequency PLL components, low noise amplifier and mixer, are located outside the human body, forming the receiver part of the system. The operating details of the proposed system were coded in Verilog-AMS. Simulation results indicate robust medical instrument tracking in 1-D. Experimental evaluation of the proposed position tracking system is also presented. The experiments described in this paper are based on a transmitter moving opposite a stationary receiver performing either constant velocity or uniformly accelerated movement, and also together with two stationary receivers performing constant velocity movement again. This latter setup is implemented in order to demonstrate the prototype's accuracy for planar (2-D) motion measurements. Error analysis and time-domain analysis are presented for system performance characterization. Furthermore, preliminary experimental assessment using a saline solution container to more closely approximate the human body as a radio frequency wave transmission medium has proved the system's capability of operating underneath the skin.


Assuntos
Catéteres , Tecnologia de Sensoriamento Remoto/instrumentação , Processamento de Sinais Assistido por Computador/instrumentação , Instrumentos Cirúrgicos , Humanos , Imagens de Fantasmas , Tecnologia de Sensoriamento Remoto/métodos
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