RESUMO
We performed 7 mm scleral pocket cataract incisions in both eyes of ten rabbits. One eye of each rabbit was closed with one interrupted 10-0 nylon suture and organic tissue glue (Tisseel) and the other was closed with a conventional shoelace running 10-0 nylon suture. The eyes were examined clinically and histopathologically at various postoperative intervals. No difference in wound integrity was found between the two closures, but slightly more inflammation occurred in the eyes closed with glue than in those closed with sutures alone. Organic tissue glue may become an alternative method to suture closure of scleral pocket cataract incisions.
Assuntos
Extração de Catarata , Adesivo Tecidual de Fibrina , Animais , Astigmatismo/etiologia , Feminino , Complicações Pós-Operatórias/etiologia , Coelhos , Esclera/patologia , Esclera/cirurgia , Técnicas de Sutura , CicatrizaçãoRESUMO
A 12-year-old boy with a supernumerary chromosome, probably derived from number 22, had typical features of Duane syndrome with limitation of abduction and retraction of the globe upon adduction. Additionally, the patient had antimongoloid slant of the eyes, epicanthal folds, preauricular sinuses, cardiac malformations, skeletal malformations, and mental retardation suggestive of the cat-eye syndrome. The cat-eye syndrome has been often associated with a supernumerary chromosome derived from number 22. Our patient's karyotype was 46,XY/47,XY, + mar, with the supernumerary chromosome probably derived from number 22. These findings supplement previous findings of chromosome 22 abnormality associated with an ocular motility disorder.
Assuntos
Transtornos Cromossômicos/diagnóstico , Fissura Palatina/diagnóstico , Síndrome da Retração Ocular/diagnóstico , Cardiopatias Congênitas/diagnóstico , Deficiência Intelectual/diagnóstico , Mosaicismo , Hipotonia Muscular/diagnóstico , Aneuploidia , Criança , Transtornos Cromossômicos/genética , Cromossomos Humanos Par 22/genética , Fissura Palatina/genética , Síndrome da Retração Ocular/genética , Anormalidades do Olho , Movimentos Oculares , Cardiopatias Congênitas/genética , Humanos , Deficiência Intelectual/genética , Cariotipagem , Masculino , Hipotonia Muscular/genéticaRESUMO
We report an 11-year-old boy with both the congenital ocular fibrosis and the Prader-Willi syndromes. Since birth he has had bilateral blepharoptosis and fixed ocular misalignment in downward gaze. Pathological examination of the extraocular muscles showed replacement by fibrous tissue. Additionally, the child had the typical clinical features of the Prader-Willi syndrome including mental retardation, hypotonia, short stature, hypogonadism, and obesity. The Prader-Willi syndrome has been consistently associated with interstitial deletions of the long arm of chromosome 15. Although our patient appeared to have normal chromosomes, he may indeed have an undetectable deletion which may be responsible for both syndromes. We believe that the gene(s) for the congenital ocular fibrosis syndrome may be located near the gene(s) for the Prader-Willi syndrome on the long arm of chromosome 15.
