1.
J Org Chem
; 72(19): 7435-8, 2007 Sep 14.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17713948
RESUMO
A new chiral benzimidazolide is developed as a nonenzymatic acylating agent for enantioselective benzoylation of racemic alpha-amino esters. The process is highly efficient, which exhibits uniformly high enantioselectivity for alpha-amino esters with or without aryl substituents under mild reaction conditions. The chiral benzimidazolide is inexpensive and is easily accessible.