[Mechanisms of the antiaggregation activity of 1,4-naphthoquinone derivatives]. / K mekhanizmu antiagregatsionnoi aktivnosti proizvodnykh 1,4-naftokhinona.

The antiaggregation effects of synthetic derivatives of 1,4-naphtoquinone and ionol were studied as compared with the antioxidant properties of the agents. The proportional relationship was shown to exist between the antiaggregation properties of the compounds and their antiradical activity under conditions of the interaction with biosubstrates. The data obtained suggest that the derivatives of 1,4-naphtoquinone with the intramolecular transfer of the charge are promising antiaggregation agents.

[Characteristics of biochemical processes of the liver in rats with various types of open-field behavior]. / Osobennosti nekotorykh biokhimicheskikh protsessov v pecheni krys s razlichnymi tipami povedeniia v otkrytom pole.

Respiration and phosphorylation of liver mitochondria, lipid spectrum of the blood serum activity of hepatocytes main microsomal enzymes were studied in outbred rats with various emotionality. It was found that in low-emotional rats, the intensity of phosphorylation processes in liver mitochondria and enzymes activity of hematocytes microsomal oxidative system responsible for detoxication processes,-- was significantly higher than in low-emotional animals. Analogous differences were found in the lipid blood spectrum and in liver mitochondria antioxidant activity of animals with different emotionality. It is supposed that there is an inter-connection between animals behaviour in the open field and the character of biochemical processes in the liver.

[Effect of 1,4-naphthoquinones on lipolysis in hemorrhagic shock]. / Vliianie nekotorykh 1,4-naftokhinonov na lipoliz pri gemorragicheskom shoke.

Derivatives of 1,4-naphthoquinones increased the lipolytic activity of epididymal and perinephric fatty tissues. A compound AK-45 Na at a dose of 30 mg/kg elevated the positive effect of rheopolyglucine on lipid metabolism, contributing to mobilization as well as to consumption of lipids in hemorrhagic shock in rats and rabbits.