Assuntos
Otopatias/etiologia , Doenças Nasais/etiologia , Vasculite/complicações , Azatioprina/uso terapêutico , Surdez/etiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Otite Média com Derrame/etiologia , Prednisolona/uso terapêutico , Vasculite/tratamento farmacológico , Vertigem/etiologiaRESUMO
In a retrospective study we have compared the toxic side effects related to the use of two antibiotic regimens in the treatment of febrile episodes in neutropenic, leukaemic patients undergoing first remission-induction. Nephrotoxicity was more severe in the gentamicin-mezlocillin (G/M) group: four patients developed oliguric renal failure and two others showed rises in the serum creatinine of more than 0.03 mmol/l. One of the two patients in the gentamicin-ticarcillin (G/T) group who showed nephrotoxicity developed renal failure. Ototoxicity and skin rashes were more commonly observed with G/M than with G/T, and the differences were statistically significant for both ototoxicity (P = 0.0004) and drug rashes (P = 0.02). The cause of the observed differences in toxicity has not been identified.
Assuntos
Gentamicinas/efeitos adversos , Leucemia/tratamento farmacológico , Mezlocilina/efeitos adversos , Doença Aguda , Adolescente , Adulto , Idoso , Combinação de Medicamentos , Toxidermias/etiologia , Orelha/efeitos dos fármacos , Feminino , Gentamicinas/administração & dosagem , Humanos , Rim/efeitos dos fármacos , Masculino , Mezlocilina/administração & dosagem , Pessoa de Meia-Idade , Ticarcilina/efeitos adversosRESUMO
A simple technique for closing small-to-medium sized perforations of the tympanic membrane in the Out-Patient Department has been described. Homograft temporalis fascia was used as a graft material. In a series of eighteen patients a closure rate of 78.2 per cent was obtained. The advantages of the method have been discussed.
Assuntos
Procedimentos Cirúrgicos Ambulatórios , Miringoplastia/métodos , Adulto , Anestésicos Locais , Seguimentos , Humanos , Pessoa de Meia-Idade , Transplante HomólogoRESUMO
PIP: From June 1970 through January 1971, a psychological comparison between 99 single white pregnant women seeking abortion and a control group of 79 single nonpregnant women of similar background showed that, as a group, the women seeking abortion were no more neurotic than nonpregnant women of the same ages. Both groups (comprised mainly of college students) were equally informed about contraceptives. 77% of the abortion group used no contraceptives prior to the pregnancy. 82% of the sexually active members of the control group consistently used contraceptives. Conscious motivational factors, such as guilt over use of contraception, reactions to loss, or severe acting-out character disorders, may have influenced the occurrence of the pregnancy in 40% of the abortion group. Psychological testing showed that the pregnant group stated themselves as more impulsive and as tending to externalize aggression.^ieng
