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2.
Spinal Cord ; 51(12): 931-3, 2013 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-24042993

RESUMO

STUDY DESIGN: Spinal tuberculosis as all other osteoarticular tuberculosis occurs as a result of hematogenous dissemination of Mycobacterium tuberculosis from a primarily infected visceral focus mainly lungs, but Pott's paraplegia occurring secondarily to Scrofuloderma has not been reported till date. PURPOSE: To document such an association of Pott's paraplegia and Scrofuloderma. METHODS: A 29-year-old female presented to us with low backache and paraplegia of 1 month duration. Clinical examination showed multiple healed Scrofuloderma lesions over sterum and neck (Figure 1). Magnetic resonance imaging (Figure 4), computed tomography (Figure 3) and X-ray (Figure 2) showed Pott's spine involving dorsal vertebrae (D8-10) with pre and paravetebral abscess with intraspinal extension. She was treated by minimally invasive surgery to drain pus and granulation tissue by resecting transverse process of D9 vertebra. Drained material was sent for histopathological examination, Zielh-neelsen (ZN) staining, culture and sensitivity for M. tuberculosis. Patient completely recovered neurologically after 1 month of surgery. RESULTS: Patient completely recovered neurologically after surgery and is presently on multidrug chemotherapy and spinal brace. CONCLUSIONS: Pott's paraplegia can occur secondary to Scrofuloderma and it can be managed by multidrug antitubercular therapy and minimally invasive surgical procedure.


Assuntos
Mycobacterium tuberculosis/fisiologia , Tuberculose Cutânea/complicações , Tuberculose da Coluna Vertebral/etiologia , Adulto , Feminino , Humanos , Imageamento por Ressonância Magnética , Tomógrafos Computadorizados , Tuberculose da Coluna Vertebral/diagnóstico , Tuberculose da Coluna Vertebral/tratamento farmacológico , Tuberculose da Coluna Vertebral/cirurgia
3.
4.
J Indian Med Assoc ; 111(3): 192-3, 2013 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-24592762

RESUMO

A cold abscess causing tracheo-oesophageal compression is quite unusual. A case of a 5-year-old boy with caries spine of D3-D4 vertebrea with respiratory distress due to mediastinal cold abscess pressing over trachea is being reported. Urgent costotransversectomy was done to decompress the cold abscess. There was immediate relief of airway compression which was evident from fall in airway pressure from 39 cm H2O to 29 cm H2O. The child was extubated on the 5th postoperative day and discharged on the 15th postoperative day in good condition.


Assuntos
Estenose Esofágica/complicações , Insuficiência Respiratória/etiologia , Vértebras Torácicas , Estenose Traqueal/complicações , Tuberculose da Coluna Vertebral/complicações , Pré-Escolar , Diagnóstico Diferencial , Estenose Esofágica/diagnóstico , Humanos , Imageamento por Ressonância Magnética , Masculino , Radiografia Torácica , Insuficiência Respiratória/diagnóstico , Estenose Traqueal/diagnóstico , Tuberculose da Coluna Vertebral/diagnóstico
5.
J Clin Orthop Trauma ; 3(2): 107-11, 2012 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26403448

RESUMO

Patellofemoral instability is initially treated conservatively and surgical treatment is reserved for resistant cases. Reconstruction of medial patellofemoral ligament has gained popularity these days as it attempts at restoring soft tissue anatomy and biomechanics of medial patellar restraint back to normal. Here we describe our novel transverse patella single tunnel and femoral interference screw technique to reconstruct the medial patellofemoral ligament using free autologous gracilis and semitendinosus grafts.

6.
J Hand Surg Eur Vol ; 33(5): 622-7, 2008 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-18977832

RESUMO

Preliminary soft tissue distraction using an external fixator before centralisation and tendon transfer of the flexor and extensor carpi ulnaris to the little finger metacarpal was used to treat Bayne's type III and IV deformities in 18 hands of 14 patients with radial club hands. Treatment with external fixator was started at a mean age of 8 (range 3-30) months. In 16 of 18 hands, the surgical treatment was completed before 10 months of age. Adequate soft tissue stretching was achieved before centralisation using fractional distraction with the external fixator in the majority of hands. After an average follow-up period of 31 months, there were seven good, eight satisfactory and one unsatisfactory result.


Assuntos
Tecido Conjuntivo/cirurgia , Fixadores Externos , Deformidades Congênitas da Mão/cirurgia , Osteogênese por Distração/instrumentação , Rádio (Anatomia)/anormalidades , Pré-Escolar , Feminino , Seguimentos , Deformidades Congênitas da Mão/diagnóstico por imagem , Deformidades Congênitas da Mão/patologia , Humanos , Lactente , Masculino , Satisfação do Paciente , Estudos Prospectivos , Radiografia , Amplitude de Movimento Articular , Resultado do Tratamento
7.
J Orthop Surg (Hong Kong) ; 15(2): 137-43, 2007 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-17709848

RESUMO

PURPOSE: To assess results of small wire external fixation using a ligamentotaxis technique for high-energy tibial plateau fractures. METHODS: Between April 2002 and May 2004, 38 consecutive patients aged 21 to 60 (mean, 32) years underwent small wire external fixation for high-energy tibial plateau fractures. 15 involved the right and 23 the left knee. 34 were closed and 4 were open injuries. Fractures were classified according to Schatzker's staging system. After a minimal of 2 years' follow-up (range, 24-42 months), each affected knee was evaluated using Rasmussen's (1) 30-point clinical grading system and (2) radiological evaluation. RESULTS: There were 22 type-VI and 16 type-V Schatzker tibial plateau fractures. Complications consisted of: 2 superficial infections, 3 pin site infections, and 4 peroneal nerve palsies. No soft tissue necrosis or devitalisation occurred. The mean range of knee movement was 132 degrees. The mean Rasmussen radiological score was 14 (range, 10-18): excellent in 6, good in 26, and fair in 6. The mean Rasmusssen functional score was 26 (range, 17-30): excellent in 19 patients, good in 17, and fair in 2. Clinical results did not parallel the radiological results. CONCLUSION: Small wire external fixation allows anatomical reconstruction of the articular surface, stable fixation of fracture fragments, early movement of the joint, and care of associated soft tissue injuries, without a high rate of complications.


Assuntos
Fios Ortopédicos , Fixadores Externos , Fixação de Fratura/instrumentação , Fraturas da Tíbia/cirurgia , Adulto , Desenho de Equipamento , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fraturas da Tíbia/diagnóstico por imagem , Tomografia Computadorizada por Raios X , Índices de Gravidade do Trauma , Resultado do Tratamento
8.
J Orthop Surg (Hong Kong) ; 15(2): 177-82, 2007 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-17709857

RESUMO

PURPOSE: To report the results of surgical management for late-presenting displaced supracondylar fractures of the humerus in children. METHODS: Between February 2002 and June 2003, 40 children (mean age, 7 years) with late presentation (range, 2-12 days) of displaced supracondylar humeral fractures were prospectively recruited. Gentle closed manipulation under image intensification was attempted in all patients, except one with a compound open fracture. Manipulation was successful in 25 patients and percutaneous skeletal stabilisation with Kirschner wires was performed. The remaining 15 patients were treated with open reduction and Kirschner wire fixation, using a mediolateral approach. RESULTS: The mean delay in presentation was approximately 4 days. No patients presenting more than 7 days after injury had the fracture reduced by closed manipulation. The mean hospital stay was 41 hours. At the final follow-up (mean, 18 months), 88% of the patients had a satisfactory result, according to Flynn's criteria. CONCLUSION: Operative treatment for late presentation of supracondylar humeral fractures in children is effective. It minimises the risk of complications and the need for continuous traction or corrective osteotomy.


Assuntos
Pinos Ortopédicos , Fixação Interna de Fraturas/instrumentação , Fraturas do Úmero/cirurgia , Criança , Articulação do Cotovelo/diagnóstico por imagem , Articulação do Cotovelo/fisiopatologia , Feminino , Seguimentos , Humanos , Fraturas do Úmero/diagnóstico por imagem , Fraturas do Úmero/fisiopatologia , Masculino , Estudos Prospectivos , Radiografia , Amplitude de Movimento Articular , Fatores de Tempo , Resultado do Tratamento
9.
J Orthop Surg (Hong Kong) ; 15(1): 109-12, 2007 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17429131

RESUMO

Acquired radial club hand caused by infection has been reported occasionally. We report a rare case of acquired radial club hand with an associated septic dislocation of the elbow, primarily caused by compartment syndrome following venous cannulation. The deformity and instability were treated with distraction using an external fixator followed by a centralisation procedure. At the 2-year follow-up the appearance and functions of the left forearm had improved considerably and the wrist was stable. There was no deterioration in ulnar growth.


Assuntos
Cateterismo Periférico/efeitos adversos , Síndromes Compartimentais/complicações , Lesões no Cotovelo , Deformidades Articulares Adquiridas/etiologia , Luxações Articulares/etiologia , Articulação do Punho , Síndromes Compartimentais/etiologia , Feminino , Humanos , Úmero/diagnóstico por imagem , Lactente , Deformidades Articulares Adquiridas/cirurgia , Radiografia , Ulna/diagnóstico por imagem , Articulação do Punho/diagnóstico por imagem , Articulação do Punho/cirurgia
10.
Ecotoxicol Environ Saf ; 68(1): 126-33, 2007 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-17166587

RESUMO

The effect of fly ash inhalation (4h daily, 5 days a week) for 28 days on the deposition of metal ions and histopathological changes in the liver and serum clinical enzymes has been studied. The results showed an increase in the concentration of metals such as cadmium (Cd), chromium (Cr), copper (Cu), manganese (Mn), and lead (Pb) in the tissues of exposed rats. The level of metals varied from metal to metal and from organ to organ. Level of serum enzymes such as serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, and alkaline phosphatase were increased in fly ash exposed rats using whole body inhalation exposure as compared to sham controls. Histopathological studies of rat liver exposed to fly ash revealed infiltration of mononuclear cells in and around the portal triads, which seems to be laden with fly ash particles. Hepatocytes showed necrotic changes such as pyknotic nuclei, karyorrhexis, and karyolytic. These changes were more towards the centrolobular areas than the midzonal and periportal areas. These findings demonstrate that the toxic metals of inhaled fly ash in rats may get translocated into extrapulmonary organs, become deposited and hence may manifest their toxic effects on different tissues.


Assuntos
Carbono/toxicidade , Resíduos Industriais/efeitos adversos , Exposição por Inalação/efeitos adversos , Fígado/efeitos dos fármacos , Material Particulado/toxicidade , Alanina Transaminase/sangue , Fosfatase Alcalina/sangue , Animais , Aspartato Aminotransferases/sangue , Cinza de Carvão , Hepatócitos/efeitos dos fármacos , Hepatócitos/patologia , Fígado/química , Fígado/metabolismo , Masculino , Metais Pesados/análise , Metais Pesados/metabolismo , Necrose/induzido quimicamente , Necrose/patologia , Ratos , Ratos Wistar
12.
Toxicol Lett ; 95(3): 165-72, 1998 May.
Artigo em Inglês | MEDLINE | ID: mdl-9704818

RESUMO

Ingestion of chromium(VI) (250, 500 or 750 ppm as potassium dichromate, K2Cr2O7) through drinking water by female rats for 3 months prior to gestation was toxic to embryo and fetus. There was a significant reduction in number of implantations and number of fetuses and an increase in number of resorptions and pre-implantation and post-implantation losses. No significant visceral abnormality was found. The increase in the number of subdermal hemorrhagic patches on the thorax and abdomen was significant. Skeletal abnormality in the form of reduced ossification in parietal, interparietal and caudal bones was observed in fetuses. Chromium levels in the blood of mothers, placenta and fetuses showed a significant increase. Duration of the estrous cycle was also increased significantly. The study revealed that long-term chromium exposure in rats did not cause embryo and fetotoxicity in a duration-dependent manner compared to short-term treatment as observed earlier. A possible explanation could be that, in the 90-day study, the female rats did not mate for three estrous cycles, thus giving time for clearance of a sizable amount of chromium from their bodies.


Assuntos
Embrião de Mamíferos/efeitos dos fármacos , Feto/efeitos dos fármacos , Dicromato de Potássio/toxicidade , Anormalidades Induzidas por Medicamentos/patologia , Animais , Peso Corporal/efeitos dos fármacos , Cromo/metabolismo , Embrião de Mamíferos/metabolismo , Desenvolvimento Embrionário e Fetal/efeitos dos fármacos , Estro/metabolismo , Feminino , Feto/metabolismo , Placenta/metabolismo , Dicromato de Potássio/farmacocinética , Gravidez , Ratos
13.
Toxicol Lett ; 89(3): 207-13, 1996 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-9001589

RESUMO

Exposure to chromium (VI) (250, 500 and 750 ppm as potassium dichromate) via drinking water pregestationally in rats revealed embryo- and fetotoxic effects in the form of a significant reduction in the number of implantations and number of fetuses. An increase in the number of resorptions, pre-implantation and post-implantation loss in chromium (VI)-treated mothers was also observed. No significant visceral abnormality was found. A significant increase in sub-dermal hemorrhagic patches on thoracic and abdominal areas was found. Skeletal abnormality in the form of reduced ossification in parietal, interparietal and caudal bones was found in the fetuses of chromium (VI)-treated mothers. Chromium levels in blood, placenta and fetuses were found to be significantly increased in the 500 ppm and 750 ppm dosed groups. The duration of estrus cycle was significantly altered after chromium (VI) exposure. This study suggests that chromium exposure in rat causes a lower degree of toxicity than in mice as observed in our earlier studies.


Assuntos
Anormalidades Induzidas por Medicamentos , Cromo/toxicidade , Desenvolvimento Embrionário e Fetal/efeitos dos fármacos , Prenhez/efeitos dos fármacos , Administração Oral , Animais , Peso Corporal/efeitos dos fármacos , Cromo/administração & dosagem , Cromo/análise , Ingestão de Líquidos , Esquema de Medicação , Implantação do Embrião/efeitos dos fármacos , Estro/efeitos dos fármacos , Feminino , Feto/química , Masculino , Placenta/química , Gravidez , Ratos
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