RESUMO
AIM: To prospectively study the influence of the uterine junctional zone thickness measured on pelvic magnetic resonance imaging (MRI), on implantation rates during in vitro fertilization (IVF). METHODS: A prospective clinical-imaging study was conducted and included 152 female patients. Patients had a positive diagnosis of infertility and an indication for IVF. All patients had a pelvic MRI scan on a 1.5T magnet with T2-weighted sequences prior to IVF. The average junctional zone thickness value and the maximal junctional zone thickness values were measured. Implantation outcomes were correlated with junctional zone values and with infertility subtypes (endometriosis, tubal, dysovulation, male, unexplained). RESULTS: The mean number of embryo transfers per patient was 1.63, with a total pregnancy rate of 54%. Junctional zone thickness increase was significantly correlated with implantation failure at IVF: implantation failure rate was 95.8% for patients with an average junctional zone superior to 7 mm and a maximal junctional zone superior to 10 mm, versus 37.5% in other patient groups (P < 0.0001), independently from the cause of infertility or patients' age. CONCLUSION: In a group of infertile patients engaged in an IVF program, a pelvic MRI scan showing a thickened uterine junctional zone is a negative predictive factor for embryo implantation after IVF.
Assuntos
Implantação do Embrião , Transferência Embrionária , Infertilidade/fisiopatologia , Infertilidade/terapia , Imageamento por Ressonância Magnética , Útero/fisiopatologia , Adulto , Feminino , Fertilização in vitro , Humanos , Modelos Logísticos , Masculino , Razão de Chances , Gravidez , Estudos Prospectivos , Resultado do TratamentoAssuntos
Adenocarcinoma/cirurgia , Antineoplásicos/administração & dosagem , Linfocele/tratamento farmacológico , Neoplasias Ovarianas/cirurgia , Peptídeos Cíclicos/administração & dosagem , Somatostatina/análogos & derivados , Feminino , Humanos , Injeções Intramusculares , Pessoa de Meia-Idade , Biópsia de Linfonodo Sentinela , Somatostatina/administração & dosagemRESUMO
Laryngeal mucous cysts are rare congenital malformations of the upper aero-digestive tract. We report one case of a ductal cyst developed in the supraglottic area. The diagnosis of an antenatal malformation was suspected on the basis of a hydramnios development during pregnancy. Ultrasound scan showed a cervical anechogen mass. This led to a fetal MRI which showed the cyst extension. A management of delivery had to be prepared due to the risk of air obstruction at the birth. The treatment consisted of a marsupialization of the cyst under laryngo-endoscopic surgery. Six months follow-up showed no recurrence.
