Assuntos
Antígenos HLA/análise , Imunoglobulinas/análise , Infecções/imunologia , Formação de Roseta , Adolescente , Criança , Pré-Escolar , Humanos , Lactente , Infecções/terapia , Osteomielite/imunologia , Osteomielite/terapia , Peritonite/imunologia , Peritonite/terapia , Pneumonia/imunologia , Pneumonia/terapia , SupuraçãoRESUMO
Experiments in guinea pigs and rabbits have shown that simultaneous immunization against influenza and tuberculosis had no effect on the reactogenic properties of both vaccines. No inhibitory effect of the BCG vaccine on the influenza virus antibody production was observed. Production of antituberculosis antibodies was the most intensive following a simultaneous immunization of animals with BCG and inactivated influenza vaccines. Both separate and simultaneous immunization conferred to animals a similar grade of protection against virulent tuberculosis mycobacteria. Application of the combined preparation "Vaxigrip" & BCG (in mixture) caused complicated local reactions and had little immunogenic effect.
Assuntos
Vacina BCG/administração & dosagem , Vacinas contra Influenza/administração & dosagem , Animais , Anticorpos Antibacterianos/biossíntese , Anticorpos Antivirais/biossíntese , Vacina BCG/farmacologia , Estudos de Avaliação como Assunto , Cobaias , Imunização , Vírus da Influenza A/imunologia , Vacinas contra Influenza/farmacologia , Mycobacterium tuberculosis/imunologia , CoelhosRESUMO
The article presents results of the treatment of children with pyo-septic diseases by method of hemosorption and lymphosorption. The experience with 86 hemosorptions and 3 lymphosorptions in 33 patients is generalized. Analysis of results of the treatment of pyo-septic conditions by extracorporal method of detoxication enabled the correlation of the effect with the course of the disease, age of the patient and the pathogenic agent of the purulent process to be detected.
Assuntos
Hemoperfusão/métodos , Sepse/terapia , Adolescente , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Recém-Nascido , Infecções por Klebsiella/terapia , Masculino , Infecções por Proteus/terapia , Infecções por Pseudomonas/terapia , Choque Séptico/terapia , Infecções Estafilocócicas/terapiaRESUMO
Following observations over 200 guinea-pigs, 48 rabbits and 105 volunteers practical data have been obtained as to an identical vaccination efficacy of BCG applied simultaneously with influenza vaccine also. The identity of local reactions to the administration of BCG and an identical post-vaccination tuberculin sensitivity have been proved. BCG immunogenicity when applied separately and simultaneously with influenza vaccines has been traced. Out of those inactivated vaccine and BCG exerted upon one another an effect intensifying antibody production. The evaluation of tuberculosis antibodies (antipolysaccharides, antiphosphatides and antiproteins) has been carried out with two serologic tests (I.H.T. and C.F.T.). After challenging animals with influenza virus and M. tuberculosis a fall of the heterogen antibody level and a stimulation of the specific antibody accumulation could be seen. The survival time, weight and correlation between antibody formation and the results of challenge have also been traced. In the observations over volunteers the absence of a negative effect of influenza vaccines following their simultaneous application with BCG has been proved. The periods and the character of the cutaneous reaction to the vaccine injection remain changed. Tuberculin sensitivity develops in an identical way.
