RESUMO
The rarity of implantation of carcinoma of the prostate is generally accepted. In the last twenty years, there have been only 6 cases reported in the literature. We add a seventh case which is unique in that the seeding occurred after biopsy and intense radiotherapy was the only mode of treatment. We recommend that a sterilizing dose of radiotherapy be given to the perineum after perineal needle biopsy.
Assuntos
Biópsia por Agulha/efeitos adversos , Inoculação de Neoplasia , Períneo/patologia , Neoplasias da Próstata/patologia , Adenocarcinoma/patologia , Adenocarcinoma/radioterapia , Adenocarcinoma/cirurgia , Dietilestilbestrol/uso terapêutico , Humanos , Masculino , Pessoa de Meia-Idade , Períneo/cirurgia , Próstata/patologia , Neoplasias da Próstata/radioterapia , Dosagem RadioterapêuticaRESUMO
Nitrofurantoin sodium and nitorfurazone, in certain critical concentrations, have the ability to immobilize spermatozoa. In this study, this effect was consisitent with both 5:1, and 10:1 dilutions. Histologic examination of the effects of these drugs as intraoperative vas irrigants revealed no apparent tissue toxicity in the guinea pig. Clinically, we found intraoperative vas irrigation with both of these nontoxic drugs to be of value in attaining azoospermia immediately postvasectomy. Therefore, they appear to be useful supplements to vasectomy.
Assuntos
Nitrofurantoína/farmacologia , Nitrofurazona/farmacologia , Motilidade dos Espermatozoides/efeitos dos fármacos , Espermatozoides/efeitos dos fármacos , Ducto Deferente/citologia , Vasectomia , Adulto , Cateterismo , Humanos , Masculino , Pessoa de Meia-Idade , Nitrofurantoína/toxicidade , Nitrofurazona/toxicidade , Irrigação Terapêutica , Ducto Deferente/efeitos dos fármacosRESUMO
In certain critical concentrations nitrofurantoin sodium and nitrofurazone cause sperm immobilization. Intraoperative was irrigation with these solutions in 16 patients produced sterility in the immediate postoperative period. This procedure minimizes time-consuming postoperative sperm analyses. Moreover, in underdeveloped countries where postoperative followup is difficult to obtain, this procedure would provide an additional positive factor in an attempt to ensure sterility.
