RESUMO
The clinical and hemodynamic effect of nitrates with both their single administration and a prolonged therapy in patients with atrioventricular block related to elecrocardiostimulation has been studied. Nitroglycerin has been found to exercise its action in two phases: first decreasing and then increasing cardiac output. The character of phase I has been ascertained to correlate with the potential development of various complications during the treatment with nitrates. A conclusion has been drawn as to the efficacy of nitrosorbid employment in the multiple modality treatment of chronic cardiac insufficiency in patients with an implanted cardiostimulator.
Assuntos
Bloqueio Cardíaco/terapia , Hemodinâmica/efeitos dos fármacos , Nitroglicerina/uso terapêutico , Marca-Passo Artificial , Débito Cardíaco/efeitos dos fármacos , Terapia Combinada , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Contração Miocárdica/efeitos dos fármacos , Resistência Vascular/efeitos dos fármacosRESUMO
A comparative study of the hemodynamic parameters in 22 patients with coronary heart disease and chronic atrioventricular block, Stage II and III, showed a favourable hemodynamic effect of atrioventricular versus ventricular electrocardiostimulation. Tests with isometric and nitroglycerin loads may be used to identify patients in the most urgent need for atrioventricular electrocardiostimulation.
Assuntos
Estimulação Cardíaca Artificial , Coração/fisiopatologia , Hemodinâmica , Idoso , Débito Cardíaco/efeitos dos fármacos , Estimulação Cardíaca Artificial/métodos , Doença Crônica , Doença das Coronárias/fisiopatologia , Doença das Coronárias/terapia , Feminino , Coração/efeitos dos fármacos , Átrios do Coração/fisiopatologia , Bloqueio Cardíaco/fisiopatologia , Bloqueio Cardíaco/terapia , Ventrículos do Coração/fisiopatologia , Hemodinâmica/efeitos dos fármacos , Humanos , Masculino , Pessoa de Meia-Idade , Nitroglicerina , Fatores de TempoRESUMO
Cardiodynamic parameters were studied in 23 patients with an implanted cardiostimulator both at rest and in conditions of an isometric exercise test. Three types of blood circulation were identified, namely eu-, hypo-, and hyperkinetic. The individual types of circulation were shown to be correlated with the severity of the clinical course of the underlying disease. The isometric exercise test allowed the researchers to differentiate between adequate and inadequate responses of hemodynamics in patients with an artificial pacemaker. It is concluded advisable to investigate the hemodynamic state of patients with an implanted artificial pacemaker so as to decide on any corrective measures that may be needed.
