The effect of different torque wrenches on rotational stiffness in compressive femoral nails: a biomechanical study.

PURPOSE: Rotation instability and locking screws failure are common problems. We aimed to determine optimal torque wrench offering maximum rotational stiffness without locking screw failure. METHODS: We used 10 conventional compression nails, 10 novel compression nails and 10 interlocking nails with 30 composite femurs. We examined rotation stiffness and fracture site compression value by load cell with 3, 6 and 8 Nm torque wrenches using torsion apparatus with a maximum torque moment of 5 Nm in both directions. Rotational stiffness of composite femur-nail constructs was calculated. RESULTS: Rotational stiffness of composite femur-compression nail constructs compressed by 6 Nm torque wrench was 3.27 ± 1.81 Nm/angle (fracture site compression: 1588 N) and 60% more than that compressed with 3 Nm torque wrench (advised previously) with 2.04 ± 0.81 Nm/angle (inter fragmentary compression: 818 N) (P = 0.000). Rotational stiffness of composite-femur-compression nail constructs compressed by 3 Nm torque wrench was 2.04 ± 0.81 Nm/angle (fracture site compression: 818 N) and 277% more than that of interlocking nail with 0.54 ± 0.08 Nm/angle (fracture site compression: 0 N) (P = 0.000). CONCLUSION: Rotational stiffness and fracture site compression value produced by 3 Nm torque wrench was not satisfactory. To obtain maximum rotational stiffness and fracture site compression value without locking screw failure, 6 Nm torque wrench in compression nails and 8 Nm torque wrench in novel compression nails should be used.

A novel nail providing more biomechanical rotational and axial stability than conventional interlocking nail in femur complex fracture model.

PURPOSE: Inter-fragmentary rotational and axial instabilities are major challenges in nailing of complex or comminuted fractures. We aimed to compare the inter-fragmentary rotational and axial stability of novel anti-rotation interlocking nail and the conventional interlocking nail in complex or comminuted femur shaft fractures. METHODS: Twenty composite femurs were divided into two groups, 30 mm was resected from the mid-portion of all composite femurs. The inter-fragmentary rotational and axial stabilities were assessed. RESULTS: Between 10-N m external and 6-N m internal rotation torques, mean maximum inter-fragmentary rotational arc motion in the novel nails was 1.63 mm and 291 % less than that of the conventional nails (6.38 mm, P = 0.000). Between 150 N distraction and 2300 N compression, mean axial motion in the novel nails was 0.8 mm and 257 % less than that of the conventional nails (2.86 mm, p = 0.000). CONCLUSION: An anti-rotational novel nail is superior to the conventional interlocking nail in terms of maximum inter-fragmentary rotational and axial stabilities in complex and comminuted femur shaft fractures.

Sarcoidosis presenting as orbital pseudotumor.

Sarcoidosis is a systemic multiorgan disorder of unknown etiology characterized by a non-caseating granuloma reaction. Ocular involvement has been reported in 25-60% of the patients. Seven percent of the patients with sarcoidosis may first see an ophthalmologist due to ocular complaints. This report aims to present our diagnostic and treatment approach to a female patient with significant unilateral lacrimal gland swelling and musculoskeletal involvement, who was diagnosed with sarcoidosis on the basis of tests and histological studies.

In vitro activity of terbinafine and itraconazole against Aspergillus species isolated from otomycosis.

The minimum inhibitory concentrations (MIC, microg ml-1) of itraconazole and terbinafine against overall 34 Aspergillus isolates from the external ear canals with otomycosis have been determined with M38-P microdilution method suggested by National Committee for Clinical Laboratory Standards (NCCLS). MIC intervals in 48 h determined by taking MIC-2 value of itraconazole (the lowest drug concentration causing 50% inhibition of visible fungal growth) and MIC-0 value of terbinafine (the lowest drug concentration causing 100% inhibition of visible fungal growth) as a basis have been found as follows: 0.125-1 and 0.06-0.5 microg ml-1 for A. niger (22 strains), 0.06-0.25 and 0.06-0.125 microg ml-1 for A. flavus (10 strains), 0.125 and 0.125-0.5 microg ml-1 for A. terreus (two strains). It has been observed that both of the antifungal agents showed an in vitro activity against all Aspergillus species tested.

Skin infection caused by Scedosporium apiospermum.

A woman with a skin infection because of Scedosporium apiospermum, in the interdigital spaces of her feet is presented. The minimum inhibition concentration values (MIC, microg ml(-1)) of this isolated mould for itraconazole, amphotericin B and terbinafine after 48 h were determined as 1, 8 and 16, respectively. The patient was treated successfully with oral terbinafine and topical clotrimazole.

The frequency of resistance to erythromycin in group A streptococci in Ankara.

UNLABELLED: The frequency of resistance to erythromycin of group A beta-haemolytic streptococci in the last 7 years was determined in three medical centres in Ankara. While all group A beta-haemolytic streptococci strains were susceptible to penicillin, a gradual increase in resistance to erythromycin until 1992 was observed. However, a substantial increase in erythromycin resistance occurred in 1993 when newer macrolides became available and were widely used in the latter part of 1992. CONCLUSION: The data show that frequent testing for resistance to erythromycin of group A beta-haemolytic streptococci is required for the use of this antibiotic in our country.