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1.
Tuberk Toraks ; 58(2): 213-28, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-20865577

RESUMO

For the prevention and control of non-communicable diseases (NCD), an action plan on NCDs is intended to support coordinated, comprehensive and integrated implementation of strategies and evidence-based interventions across individual diseases and risk factors, especially at the national and regional levels by World Health Organization (WHO). The Global Alliance against Chronic Respiratory Diseases (GARD) is making every attempt to align with WHO's non-communicable diseases action plan. GARD activities have been commenced in over 40 countries and in 11 countries an integrated NCD action plan is being prepared or has already been initiated. This integrated approach of GARD has also targeted to GARD Turkey project. The Turkish Ministry of Health has decided to apply this national control program in conformity with other NCD action plans. This article is intended to summarize these integration efforts of GARD Turkey (the National Control Program on Chronic Airway Diseases) with other NCD national programs.


Assuntos
Programas Nacionais de Saúde , Doenças Respiratórias/prevenção & controle , Organização Mundial da Saúde , Doença Crônica , Política de Saúde , Humanos , Doenças Respiratórias/patologia , Turquia
2.
Allergol Immunopathol (Madr) ; 33(4): 204-9, 2005.
Artigo em Inglês | MEDLINE | ID: mdl-16045858

RESUMO

In this study we aimed to investigate the long term effects of inhaled steroids on linear growth, adrenal function and bone mineral density. Thirty children with moderate asthma were randomly divided into two groups. Fifteen children (8 boys, 7 girls mean age; 10.6 +/- 2.1) were treated with budesonide (group 1), and 15 (9 boys, 6 girls, mean age; 9.6 +/- 2.4). with fluticasone propionate (group 2). Control group included 30 children. Anthropometric assessment, symptom and medication scores, pulmonary functions, bone mineral density, serum and urine cortisol levels and ACTH stimulation test were evaluated at the beginning of the study and after one year period. Symptom and medication scores, pulmonary functions improved significantly in both groups (p < 0.05). The mean annual growth was similar in group 1 and 2 and control group. Bone mineral density was comparable with control group at the beginning of the study and after one year. Mean serum cortisol level diminished at the end of the therapy but no significant differences were found between the initial and end values in respect to urine cortisol levels and cortisol/creatinine ratio. Of three groups ACTH stimulation test revealed that there were no significant difference between study and control groups. In conclusion, although we did not observed any side effects of inhaled corticosteroids we suggest that children treated with inhaled corticosteroids for a long time should be followed closely with respect to side effects.


Assuntos
Córtex Suprarrenal/efeitos dos fármacos , Androstadienos/efeitos adversos , Asma/tratamento farmacológico , Estatura/efeitos dos fármacos , Densidade Óssea/efeitos dos fármacos , Budesonida/efeitos adversos , Administração por Inalação , Adolescente , Córtex Suprarrenal/metabolismo , Hormônio Adrenocorticotrópico , Fosfatase Alcalina/sangue , Androstadienos/farmacologia , Androstadienos/uso terapêutico , Asma/metabolismo , Asma/fisiopatologia , Biomarcadores , Peso Corporal/efeitos dos fármacos , Budesonida/administração & dosagem , Budesonida/farmacologia , Budesonida/uso terapêutico , Cálcio/sangue , Criança , Creatinina/sangue , Feminino , Fluticasona , Humanos , Hidrocortisona/sangue , Hidrocortisona/urina , Masculino , Fósforo/sangue , Testes de Função Respiratória
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