[Ambulatory treatment of paroxysmal supraventricular arrhythmias with verapamil (isoptin)]. / Ambulatorno lechenie na pristupnite nadkamerni dizritmii s verapamil (izoptin).

Twenty patients, seven of them with paroxysmal supraventricular tachycardia; 8 with paroxysmal auricular flutter; 3 with paroxysmal auricular fibrillation and 2 with paroxysmal atrial tachycardia, with stage II of A-V block, were treated intravenously with isoptin, with an average dose of 0.1 mg/kg body mass. Ten, out of them, restored their sinus rhythm, 7 considerably slowed down the heart rate and 3 failed to respond. Adverse effects were observed only in one patient--transitory hypotension.

[Our results with the secondary prevention of myocardial infarct]. / Nashi rezultati ot vtorichna profilaktika na miokardniia infarkt.

The communication summed up the results from the two prospective follow-up care-prophylactic studies on patients with a past history of acute myocardial infarction (AMI). The first study covers all patients, with a past history of AMI and discharged in 1963, 1964, 1966 and 1967, a total of 378, with a follow-up period from 6 to 11 years. The direct task of the follow up was the prevention of a repeated infarction. The prophylactic measures, carried out with the followed-up patients were: control of body mass by a hypocaloric and antisclerotic diet, sufficient physical activity and medicamentous treatment when needed. Two groups of patients were differentiated: experimental (the patients adhering to the instructions prescribed) an control (patients that did not adhere to the recommendations for correction of body mass with no motor regimen). After the termination of the observation it was established that 12.6% from the experimental group had repeated infarction and 28.3%--in the control group. The lethality in the experimental group was 21.7% and in the control--43.9%. The second prospective observation covered 250 patients (reduced to 241 in time), with a past history of AMI and discharged within the year 1975. The follow up lasted for 5 years under the same conditions of follow-up care. Summing up our 5-year secondary prophylaxis carried out mainly with a diet, physical activity and partially with antiaggregants and medicamentous treatment when needed, we could ascertain and draw the conclusions.(ABSTRACT TRUNCATED AT 250 WORDS)

[Work capacity and motor activity of patients with a history of myocardial infarct]. / Trudosposobnost i dvigatelna aktivnost u bolni, prekarali surdechen infarkt.

A total of 241 patients with a past history of AMI were followed up with a view to the restoration of their capacity for work and its dependence on their motor activity. All deceased, 6 months after the acute infarction, were also included in the group. Work was resumed by 43,7 per cent from the whole group. But the percentage of the patients with preserved capacity for work to the age of 60 that had outlived the 5-year observation period is 75; 63, out of 84 subjects at that age, began work within an average period of 8 months after the onset of the infarction. The periods till the beginning work of our patients are longer as compared with the periods reported by foreign authors. An obvious correlation was established between the patients' capacity for work, with a past history of AMI, and their motor activity.

[Survival of patients who have had a myocardial infarct as a function of various risk factors]. / Prezhiviaemost na bolnite prekarali surdechen infarkt, v zavisimost ot niakoi riskovi faktori.

Survival was studied among 250 patients with a past history of acute myocardial infarction (AMI), followed up for 5 years. A total survival of 55,6 per cent was established. The factors affecting the survival are: age, arterial hypertension, diabetes mellitus, sex, rhythm and conduction disorders, restricted physical activity, decompensation signs after AMI, increased measurements of the heart, repeated infarction as well as the presence of anginose complaints postinfarction period. The patients, with a past history of HMI should be subjected to effective follow-up care with a view to the campaign against the factors, threatening life.

[HL-A antigens and diabetes mellitus]. / HLA antigeni i zakharen diabet.

Association of juvenile diabetes with antigen B8 and B15 was established with the comparison of the phenotype incidence of 28 HLA antigens from locus A and B among 1085 healthy control subjects and 200 patients with diabetes mellitus (74 with juvenile insulin-dependent type and 126 with insulin-independent diabetes in adults). Only the incidence of antigens B15 and Bw 21 was established to be increased in the cases of insulin-dependent type of diabetes in adults. That raises a new interest in the further study of the problem.

[Rupture of the interventricular septum in acute myocardial infarct]. / O razryve mezhzheludochkovoi peregorodki pri ostrom infarkte miokarda

The authors examined ruptures of the interventricular septum in 12 patients with acute myocardial infarction. Septal ruptures comprise 8% of all cardiac ruptures that occur within the early days of infarction, they are poorly diagnosed, and most of such patients die before the end of the 1st--5th week due to acute left-ventricular insufficiency. Characteristic features suitable for making the diagnosis are lacking. A transverse systolic murmur and "cat's purr" are important, but rare signs. Systolic murmur, maximum at the apex, is seen more often than of transverse, which makes the differential diagnosis of papillary muscle rupture still more complicated.