Management of non-palpable breast lesions detected mammographically.

A total of 212 consecutive fine-wire localization breast biopsies in 202 patients were performed on impalpable mammographically suspicious lesions. Preoperative fine-needle aspiration cytology was performed on 159 lesions and was valuable in planning the extent of the fine-wire localization biopsy. All 212 target lesions were accurately biopsied during the initial surgery. Overall, 134 lesions were malignant and 78 benign (benign:malignant ratio 1:1.72), with fewer biopsies for benign lesions performed in screened patients (benign:malignant ratio 1:2.43) than in those with symptoms (ratio 1:1). Breast conservation was achieved in 72 patients (80 per cent) with screen-detected in situ or invasive carcinoma and in 19 of 37 presenting via a symptomatic clinic. In 160 of 202 patients (79 per cent) the initial fine-wire localization biopsy was diagnostic and therapeutic.

Supraventricular tachycardia and aberration of the cardiac conduction system.

A case of a baby with supraventricular tachycardia who died is reported. Histological examination of the cardiac conduction system revealed a hypoplastic sinus node and an unusual connexion between the branching bundle and the atrioventricular node. There was no electrocardiographic evidence to suggest that the anomalous pathway functioned; the unusual configuration was probably within the normal range of morphological variations.