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1.
Biomed Pharmacother ; 162: 114624, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37018990

RESUMO

High incidence rate of cardiovascular disease (CVD) make this condition as an important public health concern. The use of natural products in treating this chronic condition has increased in recent years one of which is the single-celled green alga Chlorella. Chlorella vulgaris (CV) has been studied for its potential benefits to human health due to its biological and pharmacological features. CV contains a variety of macro and micronutrients, including proteins, omega-3, polysaccharides, vitamins, and minerals. Some studies have indicated that taking CV as a dietary supplement can help reduce inflammation and oxidative stress. In some studies, cardiovascular risk factors that are based on hematological indices did not show these benefits, and no molecular mechanisms have been identified. This comprehensive review summarized the research on the cardio-protective benefits of chlorella supplementation and the underlying molecular processes.


Assuntos
Doenças Cardiovasculares , Chlorella vulgaris , Humanos , Suplementos Nutricionais , Antioxidantes/farmacologia , Estresse Oxidativo
2.
J Med Eng Technol ; 46(4): 300-317, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35234558

RESUMO

The increasing number of studies on the behaviour of stent placement in recent decades provides a clear understanding of peripheral artery disease (PAD). The severe mechanical loads (axial tension and compression, bending, radial compression and torsion) deformation of the femoropopliteal artery (FPA) is responsible for the highest failure rate of permanent nickel-titanium (Nitinol) stents. Therefore, the purpose of this article is to review research papers that examined the deformation of the natural load environment of FPA, the properties of Nitinol and mechanical considerations. In conclusion, a better understanding of mechanical behaviour for FPA Nitinol stents contributes to increased mechanical performance and fatigue-life.


Assuntos
Artéria Poplítea , Titânio , Ligas , Artéria Femoral , Níquel , Desenho de Prótese , Stents , Resultado do Tratamento
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