RESUMO
On the basis of epidemiological study in closed children's population of Bratislava (350 000 inhabitants, out of them 70 000 children) the conclusions about falling urolithiasis incidence in children of urban population are drawn. Analysis and clinical evaluations of 287 children's patients with urolithiasis shows that in solitary calculi (in partial casts as well) the results of treatment are very good, repeated recurrences are rare. The results are considerably worse in multiple and great staghorn stones. The importance of first surgical treatment, in which all stones should be removed, as well as principles of both general and specific treatment in relationship with stone composition and metabolic disturbances are stressed.
Assuntos
Cálculos Urinários , Adolescente , Fatores Etários , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Cálculos Renais/diagnóstico , Cálculos Renais/diagnóstico por imagem , Cálculos Renais/epidemiologia , Cálculos Renais/metabolismo , Cálculos Renais/terapia , Masculino , Prognóstico , Radiografia , Fatores Sexuais , Cálculos da Bexiga Urinária/diagnóstico , Cálculos da Bexiga Urinária/epidemiologia , Cálculos da Bexiga Urinária/metabolismo , Cálculos da Bexiga Urinária/terapia , Cálculos Urinários/diagnóstico , Cálculos Urinários/diagnóstico por imagem , Cálculos Urinários/epidemiologia , Cálculos Urinários/metabolismo , Cálculos Urinários/terapiaRESUMO
In 78 patients with hypomagnesemia in urolithiasis the clinical course of disease was established in relation to therapy and dynamics of changes of serum magnesium levels. Almost 70% of patients had multiple, bilateral or recurrent nephrolithiasis or nephrocalcinosis. 70% of patients had Ca-oxalate stones or bilateral nephrocalcinosis. In 52% of patients a long-term magnesium supplementation was necessary. Significant progress of nephrolithiasis and nephrocalcinosis was observed in 80% of patients with permanent hypomagnesemia and in 4% of patients with normalization of serum magnesium level. Three of 15 patients with hypomagnesemia and progress of disease were transplanted a kidney and two were treated by hemodialysis. All five patients with renal failure had bilateral nephrocalcinosis, in three of them familiar occurrence of nephrolithiasis and hypomagnesemia was found.