1.
Phytochemistry
; 72(8): 816-20, 2011 Jun.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21397285
RESUMO
Three metabolites, pre-aurantiamine (1), (-)-9-hydroxyhexylitaconic acid (4) and (-)-9-hydroxyhexylitaconic acid-4-methyl ester (5), together with two known compounds, paraherquamide E (6) and secalonic acid D (7), were isolated from the marine-derived fungus, Aspergillus aculeatus.
Assuntos
Aspergillus/química , Dicetopiperazinas/isolamento & purificação , Succinatos/isolamento & purificação , Sequência de Bases , Dicetopiperazinas/química , Biologia Marinha , Estrutura Molecular , Piperazinas , Estereoisomerismo , Succinatos/química
2.
Phytochemistry
; 69(14): 2621-6, 2008 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-18804825
RESUMO
Nodulisporacid A (1) was isolated from a marine-derived fungus Nodulisporium sp. CRIF1, while vermelhotin (5) was obtained from an unidentified fungus CRI247-01 (a member of the Order Pleosporales). Both 1 and 5 occurred as equilibrium E/Z mixtures. Ester derivatives (2 and 3) and vermelhotin (5) showed cytotoxic activity against eleven cancer cell lines. Nodulisporacid A (1) and vermelhotin (5) exhibited moderate antiplasmodial activity.
