[The pathogenesis of respiration disorders in acute ischemia of the lower extremities and their correction using hemosorption]. / [K patogenezu dykhatel'nykh rasstroistv pri ostroi ishemii nizhnikh koneshnestei i korrektsii ikh s pomoshch'iu gemosorbtsii.

The level of hormones, metabolites, toxins and biologically active substances that reflects the degree of endogenous intoxication increases drastically in acute ischemia and revascularization of the extremity and decreases upon hemosorption (HS). This can be accounted for by their adsorption on the sorbent. According to the data of electron microscopy this pathology is accompanied by morphological signs of the "shock lung". Upon HS dystrophic and destructive changes in lung capillaries and alveolar epithelium are minimum. It is believed that surfactant release from second type pneumocytes promotes to the extension of alveoli and decrease of atelectasis. The early application of HS is pathogenetically grounded.

[Effect of plasmapheresis on histamine and serotonin levels in the blood of patients with acute pancreatitis]. / Vliianie plazmafereza na soderzhanie gistamina i serotonina v krovi u bol'nykh ostrym pankreatitom.

Alterations of histamine and serotonin levels in blood were found to depend on the duration and degree of the pathological process in the pancreas in acute pancreatitis. The effect of plasmapheresis on the content of biologically active substances in blood at different stages of the development of pancreatonecrosis was studied. It was established that plasmapheresis was an effective means to make the level of histamine and serotonin lower.