[Antigen-independent factors of the system of immunity in patients with inflammatory processes of the maxillofacial area of staphylococcal etiology]. / Sostoianie antigennezavisimykh faktorov sistemy immuniteta u bol'nykh vospalitel'nymi protsessami cheliustno-litsevoi oblasti stafilokokkovoi étiologii.

The course of severe acute and chronic odontogenic purulent inflammatory staphylococcal disorders involves the depression of cellular (myeloperoxidase, cation proteins of the neutrophilic leucocytes) and humoral (hemolytic complement and the blood serum bacteriostatic activities) antigen-independent immune factors. The differentiated immunomodulating therapy is recommended in such cases.

[Antigen-specific and antigen-nonspecific reactions of the immunity system in vaccination with a purified concentrated staphylococcal anatoxin]. / Antigenspetsificheskie i antigennespetsificheskie reaktsii sistemy immuniteta pri vaktsinatsii ochishchennym kontsentrirovannym stafilokokkovym anatoksinom.

Immunization with purified and concentrated staphylococcal toxoid leads to the rapid 12-fold rise of the level of anti-alpha-toxin and to the 17-fold rise of the titres of antibodies to extracellular staphylococcal products. At the period of immunization phasic changes in cell-mediated and humoral immunity characteristics, indicative of the state of the nonspecific resistance system, can be observed. These changes consist in the transient suppression of phagocytosis, including a decrease in the activity of intraleukocytic bactericidal systems (myeloperoxidase and cation protein), a decrease in the activity of the complement and the bactericidal activity of the blood serum, which should be taken into account when using this immune preparation for therapy.