[The efficacy of fiber bronchoscopy under outpatient polyclinic conditions]. / Effektivnost' nronkhofibroskopii v ambulatorno-poliklinicheskikh usloviiakh.

Basing on the experience of conducting 795 bronchofibroscopies under conditions of polyclinic authors discuss organized and methodological aspects ensuring maximal study safety permitting to avoid serious, danger for life complications. Pathologic changes of tracheobronchial tree were exposed in 64.6% cases, 46.5% of them--inflammations, 4.9% of cases--bronchus cancer. Morphologic cancer verification when conducting biopsy was 84.6%, when making cytologic examination of bronchial liquid-17.9%.

[Status of humoral and cellular immunity in patients with a frequently recurring form of stomach ulcer in the presence of Campylobacter pylori]. / Sostoianie gumoral'nogo i kletochnogo immuniteta u bol'nykh s chasto retsidiviruiushchei formoi iazvennoi bolezni zheludka pri nalichii Campylobacter pylori.

The findings at examination of 42 patients with gastric ulcer exhibiting frequent relapses were comparatively assessed in relation to humoral and cellular immunity, presence of mucous microflora and Campylobacter pyloridis at the ulcer site. It is shown that in the presence of Campylobacter pyloridis specific differences in the immune response were not recorded. The same results were true for mucous microflora.

[The treatment of patients with long-term nonhealing duodenal ulcers combined with chronic gastric erosions in the presence of Helicobacter pylori]. / Lechenie bol'nykh s dlitel'no ne zazhivaiushchimi iazvami dvenadtsatiperstnoi kishki v sochetanii s khronicheskimi éroziiami zheludka pri nalichii Helicobacter pylori.

Data are reported of the efficacy of different drugs in the treatment 66 patients with prolonged nonhealing duodenal ulcers in association with chronic erosions in the presence of Helicobacter pylori. It was found that a concentrate of granulocytes and de-nol proved most efficient while trichopol and furazolidone were of minor efficacy.

[Role of Campylobacter pylori and mucous microflora in the pathogenesis of long-non-healing stomach ulcers]. / Rol' Campylobacter pylori i mukoznoi mikroflory v patogeneze dlitel'no nezazhivaiushchikh iazv zheludka.

Altogether 89 patients with long non-healing gastric ulcers were examined for Campylobacter pylori (CP) and mucous microflora. It is shown that in patients with long non-healing gastric ulcers, CP was only demonstrable in 19.8% of cases whereas pathological microflora (Candida and microbial associations) in 72.3% of cases. In patients with CP, the administration of de-nol, metronidazole and ampicillin were not sufficiently effective.

[The characteristics of the clinical course of long-term nonhealing duodenal ulcers combined with chronic gastric erosion and the treatment of patients with the given pathology]. / Osobennosti klinicheskogo techeniia dlitel'no nezazhivaiushchikh iazv dvenadtsatiperstnoi kishki v sochetanii s khronicheskimi éroziiami zheludka i lecheniia bol'nykh s dannoi patologiei.

The authors provide data on the follow-up and treatment of 76 patients with slow in healing ulcers and chronic erosions. In patients with associated pathology, the clinical course of the disease is marked by a steady painful syndrome that occurs 1 to 1.5 h after meal. In the presence of Campylobacter pyloridis in these patients, the treatment schedule is to include de-nol and the concentrate of granulocytes. The use of local administration of the concentrate of granulocytes combined with hyperbaric oxygenation turned out the most effective in multimodality treatment of such patients.

[Microcirculatory disorders in patients with long-term nonhealing stomach ulcers]. / Narushenie mikrotsirkuliatsii u bol'nykh s dlitel'no nezazhivaiushchimi iazvami zheludka.

The state of systemic microcirculation according to data of biomicroscopy of the bulbar conjunctiva blood vessels was evaluated in 124 patients with prolonged nonhealing gastric ulcer and in 49 them microcirculation in the ulcer zone was assessed. It was shown that both the general and the local microcirculation showed essential disorders in this category of patients. This favoured a torpid course of the disease and requires to be considered in the treatment strategy.

[Pathogenetic mechanisms of the recurrence of chronic gastric erosions]. / Patogeneticheskie mekhanizmy retsidivov khronicheskikh érozii zheludka.

The authors investigated the mechanism of recurrent course of chronic gastric erosions. It was established that of essential importance in the recurring course of the disease is the pathological microflora, disorders of humoral immunity and local microcirculation leading to prolonged existence of a fibrinoid necrosis zone.

[Factors of protracted and recurrent course of chronic erosions of the stomach]. / Faktory zatiazhnogo i retsidiviruiushchego techeniia u bol'nykh s khronicheskimi éroziiami zheludka.

A study was made of the disease pathogenesis in 58 patients with recurrent chronic erosions of the gastric mucosa. It has been established that an important role in the relapses of the pathological process is played by pathological microflora, disturbances in humoral immunity and local microcirculation, and long existence of the zone of fibrinoid necrosis.

[Evaluation of the effectiveness of differentiated therapy in patients with chronic erosions of the gastric mucosa]. / Otsenka éffektivnosti differentsirovannoi terapii u bol'nykh khronicheskimi éroziiami slizistoi zheludka.

Potentialities of differentiated therapy of patients with recurrent chronic erosions using medicinal and nonmedicinal methods in 119 patients were studied. During differentiated therapy one should take into account the condition of pathological microflora and circulatory disturbances. At the first stage routine therapy with subsequent incorporation of biogastrone was employed. At the second stage in the absence of a therapeutic effect local administration of a granulocytic concentrate was performed, and in insufficient effectiveness, electrocoagulation of chronic erosions of the gastric mucosa was indicated. The use of differentiated therapy contributed to a favorable prognosis of disease in these patients.