[One of the methods of treatment of affective disorders in patients with alcoholism]. / Ob odnom iz metodov lecheniia affektivnykh narushenii u bol'nykh alkogolizmom.

It has been demonstrated by a double blind placebo-controlled study that transcranial electric treatment (TET) by means of combination of direct current and pulse current and pulse current at a frequency of 70-80 Hz is an effective method of correcting affective disorders (anxiety, depressions) in patients suffering from alcoholism. The therapeutic effects of TET are coupled with changes in GABA and monoamine metabolism rather than in beta-endorphin as well as with a decrease of the latent period of the occurrence of alpha-rhythm after eyes closing.

[Nonspecific resistance of the body to transcranial electric stimulation in the analgesia regimen]. / Nespetsificheskaia rezistentnost' organizma pri transkranial'nom élektricheskom vozdeistvii vrezhime analgezii.

The authors studied the level of proteins in the acute phase of inflammation and the level of glucocorticoid hormones, the leukocyte composition, the functional activity of the peripheral blood phagocytes, and the body temperature in rabbits under normal conditions and in subcutaneous turpentine injection in transcranial electric stimulation in the analgesia regimen. Changes of the studied parameters and activation of the mechanisms of the organism's nonspecific resistance occurred on a model of aseptic inflammation. It is suggested that endogenous opioid peptides play a significant role in these changes.

[Effect of the operation and general anesthesia on transcapillary exchange of fluid in the lungs during thoracic surgery]. / Vliianie operatsii i obshchei anestezii na transkapilliarnyi obmen zhidkosti v legkikh pri torakal'nykh vmeshatel'stvakh.

The influence of operation factors and general anesthesia on transcapillary exchange of liquid in the lungs was studied in 48 patients after thoracal interventions, and in 8 patients after general surgical treatment. It was found that operations on the lungs unlike general surgical procedures are characterized by the accumulation of liquid in the pulmonary interstitial tissue especially after extensive resections of lung tissue and during massive infusion-transfusion therapy. This process is influenced by the kind of general anesthesia: transcranial electroanalgesia is followed by less shifts of the transcapillary pulmonary exchange of liquid than fluoroxene narcosis.

[Effects of transcranial electrostimulation of the opioid systems on reparative processes in patients with myocardial infarct]. / Vliianie transkranial'noi élektrostimuliatsii opioidnykh sistem na reparativnye protsessy u bol'nykh infarktom miokarda.

Sixty three patients with primary excessive myocardial infarction (MI) were examined. Transcranial electric stimulation (TES) was demonstrated to contribute to more rapid formation of a postinfarction scar, development of compensatory hypertrophy of the preserved myocardium, and improvement of cardiac contractility. TES-induced activation of the endogenous opioid system was found to be one of the mechanisms responsible for stimulation of reparative processes in patients with MI. Introduction of TES into the multimodality therapy for MI improves the clinical picture of the disease, promoting diminution of circulatory failure signs and relapses of angina-associated pains and favoring decrease in the long-term course of MI and frequency of cardiac arrhythmias.

[Use of transcranial electroanalgesia for treating spondylogenic pain syndromes]. / Primenenie transkranial'noi élektroanal'gezii dlia lecheniia spondilogennykh bolevykh sindromov.

The analgesic effect of the net transcutaneous application to the brain of constant and impulse currents (the frequency of rectangular impulses was 77 Hz, the duration of an impulse, 3.5 ms) in a 2-5:1 ratio was investigated. An analgesic effect was observed in both healthy subjects and in patients with spondylogenic pain. The duration of analgesic effect following a 30-minute therapeutic session was 6-10 hours. A 5-7 session course was associated with a gradual increase and stabilization of the analgesic effect. The procedure was attended by no complications.