1.
J Org Chem
; 84(3): 1553-1562, 2019 02 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30608691
RESUMO
A new efficient synthesis of sekothrixide was established on the basis of our developed regioselective coupling of epoxy sec-alcohol with Gilman reagent guided by a TMS group. The new synthetic route allowed an overall yield of 6.3% (26 steps) from optically active 3-silyloxy-2-methylaldehyde.