Enterohemorrhagic Escherichia coli O157:H7: case report.

Enterohemorrhagic Escherichia coli (EHEC) is a significant bacterial pathogen of bloody diarrhea. Not only does it cause systemic complications, such as hemolytic uremic syndrome (HUS) (the most common cause of potentially preventable pediatric renal failure), but it also leads to large outbreaks of bloody diarrhea. Among EHEC serotypes that cause HUS, E. coli O157:H7 is the most common. Herein, we present the case of a young girl with E. coli O157:H7 infection and review the related literature.

[The rates of resistance to second-line drugs in multidrug resistant Mycobacterium tuberculosis strains]. / Cok ilaca dirençli Mycobacterium tuberculosis suslarinin minör antitüberküloz ilaçlara duyarliliginin saptanmasi.

The treatment of multidrug resistant tuberculosis (MDR-TB) requires the use of minor antituberculosis drugs, thus susceptibilities against these minor drugs should be performed. The aim of this study was to establish and standardize the susceptibility testing methods for minor antituberculosis drugs in this laboratory and to obtain data about the resistance rates. Drug susceptibility tests were performed by proportion method in Lowenstein-Jensen media for 50 MDR Mycobacterium tuberculosis isolates that have been collected from different regions of our country. Resistance rates to ethionamide, cycloserin, kanamycin, p-aminosalicylic acid, ofloxacin, thiacetasone, and capreomycin were found as 22%, 8%, 6%, 6%, 2%, 2%, and 0%, respectively. Multidrug resistance was observed in 8% of the isolates. As a result, the resistance rates of multidrug resistant M. tuberculosis strains against the tested minor antituberculosis drugs seem to be low in this study.