[Fractionation of carbon isotopes in human atherosclerotic tissues]. / Fraktsionirovanie izotopov ugleroda v tkaniiakh cheloveka pri ateroskleroze.

A decrease in heavy carbon isotope 13C content has been detected in atherosclerotically-altered aortic tissues. An extent of the isotope shift is increased with the intensification of sclerotic process in different regions of the aorta and depends on the patient's age. To explain the observed effect of isotope 13C content decrease in the altered aortic tissues it was suggested that the rates of biochemical conversions become considerably higher in sclerotically-altered tissues.

[Urgent problems of rational nutrition for the immigrant population in Arctic regions and for the natives of the North]. / Aktual'nye problemy ratsional'nogo pitaniia prishlogo naseleniia Zapoliar'ia i aborigenov Severa.

Metabolic changes in newcomers to the Asiatic North have been revealed during their adaptation to a complex of the climatic and geographic factors of high latitudes. The changes were marked by making the most of lipids and less utilization of carbohydrates in energy supply to the adaptation processes. An important role of proteins in energy supply is discussed with emphasis on the changes in vitamin metabolism. The specificity of metabolic changes during adaptation is not taken into account in the nutrition program of the newcomers. This leads to the development of disadaptation shifts in the body. An important role of nutrition in adaptation of both the newcomers and aborigines of Siberia and North is suggested. The many-century experience gained in the nutrition of aborigines should be regarded in the newcomers' nutrition programs that are recommended to be based on protein-lipid diets.

[Conditions controlling the development of distant intercellular interactions during ultraviolet radiation]. / Usloviia vozniknoveniia distantnykh mezhkletochnykh vzaimodeistvii pri UF-radiatsii.

The study is concerned with ascertaining the role of UV radiation in distant intercellular interactions (DII) and the conditions resulting in "MIRROR" CYTOPATHIC EFFECT ("M" CPE). It has been found that the UV radiation-induced extreme state of the cells in a radiant culture produces distantly in an intact detector culture, which has only an optic contact with it, the cytopathic effect (CPE) as a repercussion of a specificity of morphological manifestations imprinted in the affected culture. UV preparadiation of the detector cells aids in manifestation of the "mirror" CPE.

[Effect of several hormones on the intensity of experimental free-radical lipid oxidation reactions]. / Vliianie nekotorykh gormonov na intensivnost' reaktsii svobodnoradikal'nogo okisleniia lipidov v éksperimente.

The effect of adrenaline and hydrocortisone on the processes of free radical oxidation of lipids in rabbit erythrocytes was studied in experiment in vivo against the background of altered lipid metabolism. Adrenaline in a dose of 0.1 mg/kg and hydrocortisone in a dose of 5 mg/kg induced an increase in the amount of hydroperoxidase of fatty acids recorded by the changes of the UV spectrum. The data obtained served in confirmation of the fact that adrenaline and hydrocortisone possessed prooxidant properties, apparently mediated, this being connected with their fat mobilizing effects.

[Diurnal variations in the cellular composition of peripheral blood in mice of different genotypes]. / Sutochnye kolebaniia kletochnogo sostava perifericheskoi krovi u myshei raznykh genotipov.

Changes of the circadian rhythm of the general numbers of nucleus-containing cells and leucograms of peripheral blood in NZB mice with autoimmune spontaneous hemolytic anemia and in C57BL mice without visible disturbances in the system of immunostructural homeostasis were the most obvious in the white blood in NZB mice: a) disappearance of the circadian rhythm of the general number of nucleus-containing cells in peripheral blood owing to the inversion of circadian rhythm of the absolute number of neutrophiles; b) changes of circadian fluctuations of lymphocytes-neutrophiles ratio. The observed differences in circadian rhythms of hematological indices in NZB and C57BL mice seem to stem from insufficiency of adrenal cortex function and/or changes in functional state of hemopoietic tissue which can occur during the development of autoimmune processes.