RESUMO
Purpose@#This study was aimed to evaluate the clinical significance and prognostic value of CRP/albumin ratio (CAR) in patients with gastric cancer. @*Methods@#The data of 205 gastric cancer patients who underwent surgery was analyzed retrospectively. The association of CAR with the clinical features and prognostic value in gastric cancer was analyzed. The data of this study was combined with previous studies to further determine the prognostic value of CAR in patients with gastric cancer using a metaanalysis method. @*Results@#Cox analysis revealed that preoperative CAR was an independent prognosis indicator in patients with gastric cancer. High expression of CAR indicated a shorter survival time than in those with lower expression. CAR has a higher prognostic value in the 1-, 3-, and 5-year overall survival in patients with gastric cancer. CAR showed significant difference regarding the gastric cancer patients’ age, M stage, and clinical stage. The discriminate value of CAR in M stage of gastric cancer was high (area under the curve, 0.809). A meta-analysis combining previous data and our data showed that preoperative CAR demonstrated a significant association with the overall survival of patients with gastric cancer. @*Conclusion@#This study demonstrated that preoperative CAR could serve as an important prognostic indicator in patients with gastric cancer.
RESUMO
Purpose@#This study was aimed to evaluate the clinical significance and prognostic value of CRP/albumin ratio (CAR) in patients with gastric cancer. @*Methods@#The data of 205 gastric cancer patients who underwent surgery was analyzed retrospectively. The association of CAR with the clinical features and prognostic value in gastric cancer was analyzed. The data of this study was combined with previous studies to further determine the prognostic value of CAR in patients with gastric cancer using a metaanalysis method. @*Results@#Cox analysis revealed that preoperative CAR was an independent prognosis indicator in patients with gastric cancer. High expression of CAR indicated a shorter survival time than in those with lower expression. CAR has a higher prognostic value in the 1-, 3-, and 5-year overall survival in patients with gastric cancer. CAR showed significant difference regarding the gastric cancer patients’ age, M stage, and clinical stage. The discriminate value of CAR in M stage of gastric cancer was high (area under the curve, 0.809). A meta-analysis combining previous data and our data showed that preoperative CAR demonstrated a significant association with the overall survival of patients with gastric cancer. @*Conclusion@#This study demonstrated that preoperative CAR could serve as an important prognostic indicator in patients with gastric cancer.
RESUMO
Chopped carbon fiber-reinforced cement composite (CFRC) has become one of the potential smart materials in recent years. The key process of preparing this kind of composite at the early stage is how to disperse carbon fibers evenly into the cement matrix to achieve CFRC composite with good properties. In this study, a three-step mixing process and a six-step mixing process for the preparation of CFRC were suggested, respectively. The fracture morphology was observed by scanning electron microscopy. The influence of mass fractions of three common dispersants methyl cellulose (MC), carboxymethyl cellulose sodium (CMC) and hydroxyethyl cellulose (HEC) on the dispersion of short carbon fibers in water under certain temperature was investigated prior to the manufacture of CFRC. The correlation between mass fraction and viscosity was discussed, and the dispersion effect was assessed from the structure of dispersants and molding process. A hypothetical capsule theory was proposed to reasonably explain the dispersion effect of MC, CMC, and HEC. The experiments showed that pre-dispersion by ultrasonic vibration improved the dispersion of carbon fibers greatly. The dispersivity of carbon fibers was closely related to the category and mass fractions of dispersants. With the same mass fraction of dispersants at a certain temperature, the dispersion effect was in order of HEC > CMC > MC. Meanwhile, when the mass fraction of HEC was between 0.6 and 0.8 wt% by weight of cement and the mass fraction in the aqueous solution was between 1.65 and 1.80 wt%, carbon fibers dispersed most ideally and distributed further uniformly in the cement matrix.
