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Curr Opin Biotechnol ; 72: 8-12, 2021 12.
Artigo em Inglês | MEDLINE | ID: mdl-34365114

RESUMO

While early neural interfaces consisted of rigid, monolithic probes, recent implantable technologies include meshes, gels, and threads that imitate various properties of the neural tissue itself. Such mimicry brings new capabilities to the traditional electrophysiology toolbox, with benefits for both neuroscience studies and clinical treatments. Specifically, by matching the multi-dimensional mechanical properties of the brain, neural implants can preserve the endogenous environment while functioning over chronic timescales. Further, topological mimicry of neural structures enables seamless integration into the tissue and provides proximal access to neurons for high-quality recordings. Ultimately, we envision that neuromorphic devices incorporating functional, mechanical, and topological mimicry of the brain may facilitate stable operation of advanced brain machine interfaces with minimal disruption of the native tissue.


Assuntos
Encéfalo , Neurônios , Biomimética , Encéfalo/cirurgia , Fenômenos Eletrofisiológicos , Próteses e Implantes
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