RESUMO
Objective To optimize the method and condition s for the extraction process of Fushuning Granules.Methods Different factors and levels were in vestigated by orthogonal design wit h yields of oleanolic acid and tanshi noneⅡ A as the markers.The yields of effective com ponents by percolation and reflux we re compared.Results The extraction ratio by re-flux was higher than that by percolation.The primary factors influencin g extraction ratio by reflux were the pulverization degree of medicinal materials,concentration of alcohol,refluxing times and refluxing perio d.Conclusion The opti-mum extraction process was:refluxing and extracting the pulverized med icinal materials for 3times(1hours each time )with 6-fold 90%alcohol added in the f irst time and then 5-fold in the secon d and the third time.
RESUMO
AIM: To establish quality standard for Myricetin Dispersible Tablets. METHODS: Myricetin Dispersible Tablets were identified by UV and IR,and the content of myricetin in the tablets was determined by HPLC. RESULTS: The UV and IR spectra of Myricetin Dispersible Tablets were similar with those of myricetin.The linear range of myricetin was within the range of 0.071-0.165 mg/mL(r=(1.000 0)).The average recovery was 98.55%(n=6),and the RSD was 1.92%. CONCLUSION: The quality standard developed can be used for the quality control of Myricetin Dispersible Tablets.
