RESUMO
After Human Gene Project, studying the kinetics of DNA translocation through a nanopore, and developing a novel fast DNA sequencing technology by using nanopore have become one of the hot in gene-research). This contribution provides an overview of nanopore macromolecular identification,including bionanopore and solid-state nanopore, while the perspective of these research are also summarized.
RESUMO
We theoretically study the translocation time and the mean velocity of a long polymer threading a long nanopore on an external electric field. Theoretical method, which explicitly takes into account the nucleation theory, is presented based on the built polymer expanded model. We overcame the previous theory's defect which did not consider the real length of the pore. The present model implies that the length scale of a pore plays a very important role in the process of polymer translocation. Our calculation results are in agreement with those of previous experiments.
