RESUMO
OBJECTIVE: The objectives of this study were to examine demographic and clinicopathologic characteristics and to determine the effects of primary surgery, surgical staging and the extensiveness of staging. METHODS: In a retrospective Turkish multicenter study, 539 patients, from 14 institutions, with borderline ovarian tumors were investigated. Some of the demographic, clinical and surgical characteristics of the cases were evaluated. The effects of type of surgery, surgical staging; complete or incomplete staging on survival rates were calculated by using Kaplan-Meier method. RESULTS: The median age at diagnosis was 40 years (range 15-84) and 71.1% of patients were premenopausal. The most common histologic types were serous and mucinous. Majority of the staged cases were in Stage IA (73.5%). 242 patients underwent conservative surgery. Recurrence rates were significantly higher in conservative surgery group (8.3% vs. 3%). Of all patients in this study, 294 (54.5%) have undergone surgical staging procedures. Of the patients who underwent surgical staging, 228 (77.6%) had comprehensive staging including lymphadenectomy. Appendectomy was performed on 204 (37.8%) of the patients. The median follow-up time was 36 months (range 1-120 months). Five-year survival rate was 100% and median survival time was 120 months. Surgical staging, lymph node sampling or dissection and appendectomy didn't cause any difference on survival. CONCLUSION: Comprehensive surgical staging, lymph node sampling or dissection and appendectomy are not beneficial in borderline ovarian tumors surgical management.
Assuntos
Neoplasias Ovarianas/patologia , Neoplasias Ovarianas/cirurgia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Apendicectomia , Feminino , Humanos , Estimativa de Kaplan-Meier , Excisão de Linfonodo , Linfonodos/patologia , Linfonodos/cirurgia , Metástase Linfática , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/epidemiologia , Recidiva Local de Neoplasia/patologia , Estadiamento de Neoplasias , Neoplasias Ovarianas/epidemiologia , Estudos Retrospectivos , Turquia/epidemiologia , Adulto JovemRESUMO
BACKGROUND: Twin pregnancies located in the separate horns of a bicornuate uterus following in vitro fertilization and embryo transfer have been rarely reported. CASE: A 32-year-old woman presented with primary infertility and was diagnosed as having a bicornuate uterus. Because of severe male factor infertility, in vitro fertilization and embryo transfer were recommended. Embryo transfer resulted in a twin pregnancy with a fetus in each horn. CONCLUSION: Embryo transfer into separate uterine cavities resulted in a twin pregnancy, with a fetus in each horn, and term delivery. Split embryo transfer into each uterine cavity of an uncorrected bicornuate uterus is a feasible treatment option in selected patients, provided that the couple is counseled about the risks involved.
