1.
Am J Gastroenterol
; 93(10): 1960-2, 1998 Oct.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9772065
RESUMO
We present the case history of a 22-yr-old woman diagnosed with ischemic colitis associated with the use of oral contraceptives (OC). At the time of her presenting symptoms activated protein C (APC) resistance, a risk factor for thrombosis, was demonstrated. There was no laboratory evidence of inherited thrombophilia; that is, antithrombin III, protein C and protein S levels were normal and the factor V Leiden mutation was not present. The OC were discontinued and the patient's symptoms improved. Subsequent evaluation revealed that the activated protein C resistance had resolved. This case illustrates APC resistance as a potential link between OC use and its known association with ischemic colitis.
Assuntos
Colite Isquêmica/induzido quimicamente , Anticoncepcionais Orais Combinados/efeitos adversos , Combinação Etinil Estradiol e Norgestrel/efeitos adversos , Proteína C , Adulto , Testes de Coagulação Sanguínea , Colite Isquêmica/sangue , Fator V/genética , Feminino , Humanos , Mutação , Proteína C/fisiologia
2.
Dig Dis
; 15(4-5): 312, 1997.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9359019